SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B6YRS4

- SYL_AZOPC

UniProt

B6YRS4 - SYL_AZOPC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, CFPG_633
Organism
Azobacteroides pseudotrichonymphae genomovar. CFP2
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei695 – 6951ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAZO511995:GKF1-671-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:CFPG_633
OrganismiAzobacteroides pseudotrichonymphae genomovar. CFP2
Taxonomic identifieri511995 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesCandidatus Azobacteroides
ProteomesiUP000000723: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 918918Leucine--tRNA ligaseUniRule annotation
PRO_1000091288Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi511995.CFPG_633.

Structurei

3D structure databases

ProteinModelPortaliB6YRS4.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionUniRule annotation
Add
BLAST
Motifi692 – 6965"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiKGNPLES.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 4 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

B6YRS4-1 [UniParc]FASTAAdd to Basket

« Hide

MKYDFDAIEK KWQKYWKENR TYQVNIDRNK PKYYVLDMFP YPSGVGLHVG    50
HPLGYIASDI YARYKRLKGF NVLHPMGYDA YGLPAEQYAI QTGQHPSITT 100
KENINRYRKQ LDKIGFCFDW DREIRTCDPK YYQWTQWVFI QMFNSYYCKE 150
AQRARPITEL VKILENQGTG GLHLACTKEI HLTANEWQMK DEKSKQAILM 200
NYRIAYLSDI VVNWCPALGT VLANDEISGG ISIRGGYTVE QRKMRQWCLR 250
ISAYAKRLLE GLDKIEWTDS LKKMQRNWIG RSEGVELRFK IKDENIEFMI 300
FTTRPETIFG VTFIVIAPES EWLTQTIISK KKDSVDSYLN LVKRRTERER 350
ISNRKVTGVF TGSYAVHPIS GETIPIWISD YILADYGTGA VMAVPAHDSR 400
DYAFAKHFDL PIIPLIEDID ISKESFDIKE GIMTNSDFLN GLSVKQAIQK 450
VKEYIKDENL GKIKVNYRLR DAIFSRQRYW GEPFPIYYKN GIPYAVDEED 500
LPIKLPEIDK FLPAETGKPP LGRAKNWTYK GYPLELTTMP GFAGSSAYYL 550
RYEDPHNSEC LVSSEANEYW QNVDLYIGGI EHATGHLIYS RFWNKFLFDL 600
GIVAKEEPFK KLINQGMIQG RSNFVYRIKN TNTFVSYGLK HQYDVTPIHV 650
DINLVFDDVL NIESFRDWNS EYKNAEFILE NGKYVCGWAI EKMSKSMFNT 700
VSPDNIVNRF GADAFRLYEM FLGPLEQSKP WDTKGIDGIA RFLKRLWNLF 750
FENDVLKVSN SLPLDKELKS IHKLIKKVSW DIENFSFNTS VAAFMICINE 800
LTLLKCSKHS ILSDLVIVLA PFAPHIAEEL WHLLGNEATI FDSQFPKCNE 850
EYLKEENVKY TVSFNGKARF ILNFPKKISE ENVKDTVLKC ESSKKWLKNK 900
IPKKIIIIPN KIVNIVFD 918
Length:918
Mass (Da):106,760
Last modified:January 20, 2009 - v1
Checksum:i708D3B4BAD69121D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP010656 Genomic DNA. Translation: BAG83896.1.
RefSeqiYP_002309307.1. NC_011565.1.

Genome annotation databases

EnsemblBacteriaiBAG83896; BAG83896; CFPG_633.
GeneIDi7039386.
KEGGiaps:CFPG_633.
PATRICi31963194. VBICanAzo57536_0950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP010656 Genomic DNA. Translation: BAG83896.1 .
RefSeqi YP_002309307.1. NC_011565.1.

3D structure databases

ProteinModelPortali B6YRS4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 511995.CFPG_633.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAG83896 ; BAG83896 ; CFPG_633 .
GeneIDi 7039386.
KEGGi aps:CFPG_633.
PATRICi 31963194. VBICanAzo57536_0950.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi KGNPLES.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci CAZO511995:GKF1-671-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 4 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut."
    Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M.
    Science 322:1108-1109(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiSYL_AZOPC
AccessioniPrimary (citable) accession number: B6YRS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 20, 2009
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi