Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B6YRB0

- PNP_AZOPC

UniProt

B6YRB0 - PNP_AZOPC

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Azobacteroides pseudotrichonymphae genomovar. CFP2
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (20 Jan 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi490 – 4901MagnesiumUniRule annotation
    Metal bindingi496 – 4961MagnesiumUniRule annotation

    GO - Molecular functioni

    1. 3'-5'-exoribonuclease activity Source: InterPro
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    4. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP
    2. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciCAZO511995:GKF1-500-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:CFPG_469
    OrganismiAzobacteroides pseudotrichonymphae genomovar. CFP2
    Taxonomic identifieri511995 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesCandidatus Azobacteroides
    ProteomesiUP000000723: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 719719Polyribonucleotide nucleotidyltransferasePRO_1000147882Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi511995.CFPG_469.

    Structurei

    3D structure databases

    ProteinModelPortaliB6YRB0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini557 – 61963KHUniRule annotationAdd
    BLAST
    Domaini629 – 69971S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    HOGENOMiHOG000218326.
    KOiK00962.
    OMAiGTENTIC.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF13014. KH_3. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B6YRB0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MINSIIKTID LGDGRTITLE TGKLAKQADG AIVLRMNNTM ILATVCVAKD    50
    TNPCVDFLPL QVEYKEKFSA FGRFPGGFTK REGRASDYEI LTCRLIDRTL 100
    RPLFPRDYHS EVFVNIILFS SDGEDIPDAL AGLAASAALS VSTIPFNGPI 150
    SEVRVARIDG KFKINPTFGE LAKADMDIMV GATADNIMMV EGEMNEVSEE 200
    EMLEAIKAAH EAIKPQCKAQ IELARIVGTT IKNTYSHEVN DEELRSDIKT 250
    KLYDKVYAVA KSGQCKNKRI EAFQTIIEEY KKQFKEKELS EEKIFLIKRY 300
    YYEIEKEVMR RCILDENIRI DGRKTTEIRP IWSEVNPITG PHGSAIFTRG 350
    ETQALATVTL GTKLNEKIID DVLINDKERF LLHYNFPPFA TGEARAQRGI 400
    GRREIGHGNL AHRALKPIIP NNYPYVIRVV SDILESNGSS SMATVCAGTL 450
    SLMDAGVQIK RPVSGIAMGL IFEKEGSKYA ILSDILGDED HLGDMDFKVA 500
    GTKKGITATQ MDIKIDGLSY EVLERALSQA KQGREYILDK MLETIPEPRT 550
    DLKPHTPKIE IIIIPKEFIG SVIGPGGKII QRLQEETGTT ITIEEIEKMG 600
    RIEIFGDNKK SIDAALTRIK GIVSVPEVGE IYEGKIRSIM PYGAFIEFLP 650
    GKEGLLHISE ISWKHLESIE EAGLNEGDFI KIKLVDIDSK TGKFKLSHKI 700
    LLPHSEKYTA IRREQHEKI 719
    Length:719
    Mass (Da):80,337
    Last modified:January 20, 2009 - v1
    Checksum:i37E96CF647AF6FEB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010656 Genomic DNA. Translation: BAG83732.1.
    RefSeqiWP_012573493.1. NC_011565.1.
    YP_002309143.1. NC_011565.1.

    Genome annotation databases

    EnsemblBacteriaiBAG83732; BAG83732; CFPG_469.
    GeneIDi7039667.
    KEGGiaps:CFPG_469.
    PATRICi31962726. VBICanAzo57536_0723.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010656 Genomic DNA. Translation: BAG83732.1 .
    RefSeqi WP_012573493.1. NC_011565.1.
    YP_002309143.1. NC_011565.1.

    3D structure databases

    ProteinModelPortali B6YRB0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 511995.CFPG_469.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG83732 ; BAG83732 ; CFPG_469 .
    GeneIDi 7039667.
    KEGGi aps:CFPG_469.
    PATRICi 31962726. VBICanAzo57536_0723.

    Phylogenomic databases

    eggNOGi COG1185.
    HOGENOMi HOG000218326.
    KOi K00962.
    OMAi GTENTIC.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci CAZO511995:GKF1-500-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF13014. KH_3. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut."
      Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M.
      Science 322:1108-1109(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPNP_AZOPC
    AccessioniPrimary (citable) accession number: B6YRB0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: January 20, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3