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B6VNV2

- B6VNV2_HUMAN

UniProt

B6VNV2 - B6VNV2_HUMAN

Protein
Submitted name:

Truncated antigen peptide transporter 2

Gene

TAP2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
    2. ATP binding Source: InterPro
    3. peptide transporter activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Truncated antigen peptide transporter 2Imported
    Gene namesi
    Name:TAP2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiB6VNV2.
    BgeeiB6VNV2.

    Family & Domainsi

    Family and domain databases

    InterProiIPR011527. ABC1_TM_dom.
    IPR013306. ABC_B3.
    [Graphical view]
    PRINTSiPR01897. TAP2PROTEIN.
    SUPFAMiSSF90123. SSF90123. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B6VNV2-1 [UniParc]FASTAAdd to Basket

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    MRLPDLRPWT SLLLVDAALL WLLQGPLGTL LPQGLPGLWL EGTLRLGGLW    50
    GLLKLRGLLG FVGTLLLPLC LATPLTVSLR ALVAGASRAP PARVASAPWS 100
    WLLVGYGAAG LSWSLWAVLS PPGAQEKEQD QVNNKVLMWR LLKLSRPDLP 150
    LLVAAFFFLV LAVLGETLIP HYSGRVIDIL GGDFDPHAFA SAIFFMCLFS 200
    FGSSLSAGC 209
    Length:209
    Mass (Da):22,450
    Last modified:December 16, 2008 - v1
    Checksum:iF673ECE5F1C10127
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM246456 mRNA. Translation: CAR92541.1.
    UniGeneiHs.502.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM246456 mRNA. Translation: CAR92541.1 .
    UniGenei Hs.502.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    NextBioi 35478476.

    Gene expression databases

    ArrayExpressi B6VNV2.
    Bgeei B6VNV2.

    Family and domain databases

    InterProi IPR011527. ABC1_TM_dom.
    IPR013306. ABC_B3.
    [Graphical view ]
    PRINTSi PR01897. TAP2PROTEIN.
    SUPFAMi SSF90123. SSF90123. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "A novel mutation in the TAP2 gene in bare lymphocyte syndrome leading to metastatic squamous cell carcinoma of skin."
      Gonzalez-Santesteban C.P., Espana A., de la Calle-Martin O.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Molecular analysis of the mutant CD8 glycoprotein responsible for familial CD8 deficiency."
      Gonzalez-Santesteban C.P.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. De La Calle-Martin O.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiB6VNV2_HUMAN
    AccessioniPrimary (citable) accession number: B6VNV2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 16, 2008
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.