Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Truncated antigen peptide transporter 2

Gene

TAP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
  2. ATP binding Source: InterPro
  3. peptide transporter activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Truncated antigen peptide transporter 2Imported
Gene namesi
Name:TAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB6VNV2.
ExpressionAtlasiB6VNV2. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR011527. ABC1_TM_dom.
IPR005293. Tap2/ABCB3.
[Graphical view]
PANTHERiPTHR24221:SF160. PTHR24221:SF160. 1 hit.
PRINTSiPR01897. TAP2PROTEIN.
SUPFAMiSSF90123. SSF90123. 1 hit.

Sequencei

Sequence statusi: Complete.

B6VNV2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLPDLRPWT SLLLVDAALL WLLQGPLGTL LPQGLPGLWL EGTLRLGGLW
60 70 80 90 100
GLLKLRGLLG FVGTLLLPLC LATPLTVSLR ALVAGASRAP PARVASAPWS
110 120 130 140 150
WLLVGYGAAG LSWSLWAVLS PPGAQEKEQD QVNNKVLMWR LLKLSRPDLP
160 170 180 190 200
LLVAAFFFLV LAVLGETLIP HYSGRVIDIL GGDFDPHAFA SAIFFMCLFS

FGSSLSAGC
Length:209
Mass (Da):22,450
Last modified:December 16, 2008 - v1
Checksum:iF673ECE5F1C10127
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM246456 mRNA. Translation: CAR92541.1.
UniGeneiHs.502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM246456 mRNA. Translation: CAR92541.1.
UniGeneiHs.502.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35478476.

Gene expression databases

BgeeiB6VNV2.
ExpressionAtlasiB6VNV2. baseline and differential.

Family and domain databases

InterProiIPR011527. ABC1_TM_dom.
IPR005293. Tap2/ABCB3.
[Graphical view]
PANTHERiPTHR24221:SF160. PTHR24221:SF160. 1 hit.
PRINTSiPR01897. TAP2PROTEIN.
SUPFAMiSSF90123. SSF90123. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A novel mutation in the TAP2 gene in bare lymphocyte syndrome leading to metastatic squamous cell carcinoma of skin."
    Gonzalez-Santesteban C.P., Espana A., de la Calle-Martin O.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular analysis of the mutant CD8 glycoprotein responsible for familial CD8 deficiency."
    Gonzalez-Santesteban C.P.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. De La Calle-Martin O.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB6VNV2_HUMAN
AccessioniPrimary (citable) accession number: B6VNV2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 7, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.