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B6VNV2

- B6VNV2_HUMAN

UniProt

B6VNV2 - B6VNV2_HUMAN

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Protein
Submitted name:

Truncated antigen peptide transporter 2

Gene

TAP2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
  2. ATP binding Source: InterPro
  3. peptide transporter activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Truncated antigen peptide transporter 2Imported
Gene namesi
Name:TAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB6VNV2.
ExpressionAtlasiB6VNV2. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR011527. ABC1_TM_dom.
IPR013306. ABC_B3.
[Graphical view]
PRINTSiPR01897. TAP2PROTEIN.
SUPFAMiSSF90123. SSF90123. 1 hit.

Sequencei

Sequence statusi: Complete.

B6VNV2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRLPDLRPWT SLLLVDAALL WLLQGPLGTL LPQGLPGLWL EGTLRLGGLW
60 70 80 90 100
GLLKLRGLLG FVGTLLLPLC LATPLTVSLR ALVAGASRAP PARVASAPWS
110 120 130 140 150
WLLVGYGAAG LSWSLWAVLS PPGAQEKEQD QVNNKVLMWR LLKLSRPDLP
160 170 180 190 200
LLVAAFFFLV LAVLGETLIP HYSGRVIDIL GGDFDPHAFA SAIFFMCLFS

FGSSLSAGC
Length:209
Mass (Da):22,450
Last modified:December 16, 2008 - v1
Checksum:iF673ECE5F1C10127
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM246456 mRNA. Translation: CAR92541.1.
UniGeneiHs.502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM246456 mRNA. Translation: CAR92541.1 .
UniGenei Hs.502.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

NextBioi 35478476.

Gene expression databases

Bgeei B6VNV2.
ExpressionAtlasi B6VNV2. baseline and differential.

Family and domain databases

InterProi IPR011527. ABC1_TM_dom.
IPR013306. ABC_B3.
[Graphical view ]
PRINTSi PR01897. TAP2PROTEIN.
SUPFAMi SSF90123. SSF90123. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A novel mutation in the TAP2 gene in bare lymphocyte syndrome leading to metastatic squamous cell carcinoma of skin."
    Gonzalez-Santesteban C.P., Espana A., de la Calle-Martin O.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular analysis of the mutant CD8 glycoprotein responsible for familial CD8 deficiency."
    Gonzalez-Santesteban C.P.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. De La Calle-Martin O.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB6VNV2_HUMAN
AccessioniPrimary (citable) accession number: B6VNV2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.