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B6VJS3

- B6VJS3_MOUSE

UniProt

B6VJS3 - B6VJS3_MOUSE

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Protein
Submitted name: 5-hydroxytryptamine receptor 7
Gene
Htr7
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serotonin receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. circadian rhythm Source: InterPro
  2. smooth muscle contraction Source: InterPro
  3. synaptic transmission Source: InterPro
  4. vasoconstriction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine receptor 7Imported
Gene namesi
Name:Htr7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 19

Organism-specific databases

MGIiMGI:99841. Htr7.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriB6VJS3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025712.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00750000117429.
HOGENOMiHOG000239242.
HOVERGENiHBG106962.
KOiK04163.
OMAiPTWDAPP.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR001069. 5HT_7_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00652. 5HT7RECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6VJS3-1 [UniParc]FASTAAdd to Basket

« Hide

MMDVNSSGRP DLYGHLRSLI LPEVGRRLQD LSPDGGAHSV VSSWMPHLLS    50
GFPEVTASPA PTWDAPPDNV SGCGEQINYG RVEKVVIGSI LTLITLLTIA 100
GNCLVVISVC FVKKLRQPSN YLIVSLALAD LSVAVAVMPF VSVTDLIGGK 150
WIFGHFFCNV FIAMDVMCCT ASIMTLCVIS IDRYLGITRP LTYPVRQNGK 200
CMAKMILSVW LLSASITLPP LFGWAQNVND DKVCLISQDF GYTIYSTAVA 250
FYIPMSVMLF MYYQIYKAAR KSAAKHKFSG FPRVQPESVI SLNGVVKLQK 300
EVEECANLSR LLKHERKNIS IFKREQKAAT TLGIIVGAFT VCWLPFFLLS 350
TARPFICGTS CSCIPLWVER TCLWLGYANS LINPFIYAFF NRDLRTTYRS 400
LLQCQYRNIN RKLSAAGMHE ALKLAERPER SEFVLMTGAS GVQKALENLP 450
WGNGVNTGIK AVNSVALTKL 470
Length:470
Mass (Da):52,013
Last modified:December 16, 2008 - v1
Checksum:iA36F839B7550F044
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC133874 Genomic DNA. No translation available.
FM178516 mRNA. Translation: CAQ76702.1.
RefSeqiXP_006526764.1. XM_006526701.1.
UniGeneiMm.254266.

Genome annotation databases

EnsembliENSMUST00000099505; ENSMUSP00000097105; ENSMUSG00000024798.
GeneIDi15566.
KEGGimmu:15566.
UCSCiuc012bkx.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC133874 Genomic DNA. No translation available.
FM178516 mRNA. Translation: CAQ76702.1 .
RefSeqi XP_006526764.1. XM_006526701.1.
UniGenei Mm.254266.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000025712.

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000099505 ; ENSMUSP00000097105 ; ENSMUSG00000024798 .
GeneIDi 15566.
KEGGi mmu:15566.
UCSCi uc012bkx.1. mouse.

Organism-specific databases

CTDi 3363.
MGIi MGI:99841. Htr7.

Phylogenomic databases

GeneTreei ENSGT00750000117429.
HOGENOMi HOG000239242.
HOVERGENi HBG106962.
KOi K04163.
OMAi PTWDAPP.

Miscellaneous databases

NextBioi 35547190.
SOURCEi Search...

Gene expression databases

Genevestigatori B6VJS3.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR001069. 5HT_7_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00652. 5HT7RECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, genomic organization and functionality of 5-HT(7) receptor splice variants in mouse brain."
    Gellynck E., Laenen K., Andressen K.W., Lintermans B., De Martelaere K., Matthys A., Levy F.O., Haegeman G., Vanhoenacker P., Van Craenenbroeck K.
    Gene 426:23-31(2008)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/CImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB6VJS3_MOUSE
AccessioniPrimary (citable) accession number: B6VJS3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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