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B6VJS3

- B6VJS3_MOUSE

UniProt

B6VJS3 - B6VJS3_MOUSE

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Protein
Submitted name:

5-hydroxytryptamine receptor 7

Gene

Htr7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serotonin receptor activity Source: InterPro

GO - Biological processi

  1. circadian rhythm Source: InterPro
  2. smooth muscle contraction Source: InterPro
  3. synaptic transmission Source: InterPro
  4. vasoconstriction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine receptor 7Imported
Gene namesi
Name:Htr7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 19

Organism-specific databases

MGIiMGI:99841. Htr7.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriB6VJS3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025712.

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118795.
HOGENOMiHOG000239242.
HOVERGENiHBG106962.
KOiK04163.
OMAiPTWDAPP.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR001069. 5HT_7_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00652. 5HT7RECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6VJS3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMDVNSSGRP DLYGHLRSLI LPEVGRRLQD LSPDGGAHSV VSSWMPHLLS
60 70 80 90 100
GFPEVTASPA PTWDAPPDNV SGCGEQINYG RVEKVVIGSI LTLITLLTIA
110 120 130 140 150
GNCLVVISVC FVKKLRQPSN YLIVSLALAD LSVAVAVMPF VSVTDLIGGK
160 170 180 190 200
WIFGHFFCNV FIAMDVMCCT ASIMTLCVIS IDRYLGITRP LTYPVRQNGK
210 220 230 240 250
CMAKMILSVW LLSASITLPP LFGWAQNVND DKVCLISQDF GYTIYSTAVA
260 270 280 290 300
FYIPMSVMLF MYYQIYKAAR KSAAKHKFSG FPRVQPESVI SLNGVVKLQK
310 320 330 340 350
EVEECANLSR LLKHERKNIS IFKREQKAAT TLGIIVGAFT VCWLPFFLLS
360 370 380 390 400
TARPFICGTS CSCIPLWVER TCLWLGYANS LINPFIYAFF NRDLRTTYRS
410 420 430 440 450
LLQCQYRNIN RKLSAAGMHE ALKLAERPER SEFVLMTGAS GVQKALENLP
460 470
WGNGVNTGIK AVNSVALTKL
Length:470
Mass (Da):52,013
Last modified:December 16, 2008 - v1
Checksum:iA36F839B7550F044
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133874 Genomic DNA. No translation available.
FM178516 mRNA. Translation: CAQ76702.1.
RefSeqiXP_006526764.1. XM_006526701.1.
UniGeneiMm.254266.

Genome annotation databases

EnsembliENSMUST00000099505; ENSMUSP00000097105; ENSMUSG00000024798.
GeneIDi15566.
KEGGimmu:15566.
UCSCiuc012bkx.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133874 Genomic DNA. No translation available.
FM178516 mRNA. Translation: CAQ76702.1 .
RefSeqi XP_006526764.1. XM_006526701.1.
UniGenei Mm.254266.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000025712.

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000099505 ; ENSMUSP00000097105 ; ENSMUSG00000024798 .
GeneIDi 15566.
KEGGi mmu:15566.
UCSCi uc012bkx.1. mouse.

Organism-specific databases

CTDi 3363.
MGIi MGI:99841. Htr7.

Phylogenomic databases

GeneTreei ENSGT00760000118795.
HOGENOMi HOG000239242.
HOVERGENi HBG106962.
KOi K04163.
OMAi PTWDAPP.

Miscellaneous databases

NextBioi 35547190.
SOURCEi Search...

Gene expression databases

Genevestigatori B6VJS3.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR001069. 5HT_7_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00652. 5HT7RECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, genomic organization and functionality of 5-HT(7) receptor splice variants in mouse brain."
    Gellynck E., Laenen K., Andressen K.W., Lintermans B., De Martelaere K., Matthys A., Levy F.O., Haegeman G., Vanhoenacker P., Van Craenenbroeck K.
    Gene 426:23-31(2008)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/CImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB6VJS3_MOUSE
AccessioniPrimary (citable) accession number: B6VJS3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3