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Protein

Sec-independent protein translocase protein TatB

Gene

tatC

Organism
Helicobacter pylori (strain P12)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, TranslocationUniRule annotationSAAS annotation, Transport

Enzyme and pathway databases

BioCyciHPYL570508:GJ8D-397-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatBUniRule annotationSAAS annotation
Gene namesi
Name:tatCImported
Synonyms:tatBUniRule annotation
Ordered Locus Names:HPP12_0384Imported
OrganismiHelicobacter pylori (strain P12)Imported
Taxonomic identifieri570508 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000008198 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotationSAAS annotation

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili82 – 10928Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TatB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000245366.
KOiK03117.
OMAiATDNNTK.

Family and domain databases

HAMAPiMF_00237. TatB. 1 hit.
InterProiIPR018448. TatB.
IPR003998. TatB-like.
[Graphical view]
PRINTSiPR01506. TATBPROTEIN.
TIGRFAMsiTIGR01410. tatB. 1 hit.

Sequencei

Sequence statusi: Complete.

B6JKW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFGMGFFEIL VVLVVAIIFL GPEKFPQAVV DVVKFFRAVK KTLNDAKDTL
60 70 80 90 100
DKEINIEEIK KETLEYQKLF ENKVESLKGV KIEELEDAKI TAENEIKSIQ
110 120 130 140 150
DLMQDYQQSL ENNAPPNHSN KEVSNEEALN KEVSSDEPPK EVQLATDNNA
160
KEHDKEKEHV
Length:160
Mass (Da):18,289
Last modified:December 16, 2008 - v1
Checksum:i1554DC481572AE70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001217 Genomic DNA. Translation: ACJ07541.1.
RefSeqiWP_000467608.1. NC_011498.1.

Genome annotation databases

EnsemblBacteriaiACJ07541; ACJ07541; HPP12_0384.
KEGGihpp:HPP12_0384.
PATRICi20608730. VBIHelPyl2824_0406.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001217 Genomic DNA. Translation: ACJ07541.1.
RefSeqiWP_000467608.1. NC_011498.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACJ07541; ACJ07541; HPP12_0384.
KEGGihpp:HPP12_0384.
PATRICi20608730. VBIHelPyl2824_0406.

Phylogenomic databases

HOGENOMiHOG000245366.
KOiK03117.
OMAiATDNNTK.

Enzyme and pathway databases

BioCyciHPYL570508:GJ8D-397-MONOMER.

Family and domain databases

HAMAPiMF_00237. TatB. 1 hit.
InterProiIPR018448. TatB.
IPR003998. TatB-like.
[Graphical view]
PRINTSiPR01506. TATBPROTEIN.
TIGRFAMsiTIGR01410. tatB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB6JKW3_HELP2
AccessioniPrimary (citable) accession number: B6JKW3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.