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B6JI64 (B6JI64_OLICO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333

Short name=Coprogen oxidase HAMAP MF_00333
Short name=Coproporphyrinogenase HAMAP MF_00333
EC=1.3.3.3 HAMAP MF_00333
Gene names
Name:hemF HAMAP MF_00333 EMBL ACI94108.1
Ordered Locus Names:OCA5_c10900 EMBL AEI05809.1, OCAR_7000
OrganismOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]
Taxonomic identifier504832 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. SAAS SAAS018375 HAMAP MF_00333

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. SAAS SAAS018375 HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. SAAS SAAS018375 HAMAP MF_00333

Subunit structure

Homodimer By similarity. SAAS SAAS018375 HAMAP MF_00333

Subcellular location

Cytoplasm By similarity HAMAP MF_00333.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family. HAMAP MF_00333

Sequences

Sequence LengthMass (Da)Tools
B6JI64 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: 3DC9E6C9DE77511A

FASTA29533,695
        10         20         30         40         50         60 
MDAPLLENRK TTARAWFEKL RDDICVSYER LEDEAPASLY GDQAGRFERK AWERTDHTGA 

        70         80         90        100        110        120 
PGGGGMMSMM RGRLFEKVGV HCSTVFGEFA PEFRAQIPGA ADDPRFWASG ISLIAHPRNP 

       130        140        150        160        170        180 
NVPAVHMNTR FVVTTKRWFG GGADLTPVLE RRRTQEDSDT IAFHEAFRKT CHAHAAVAPY 

       190        200        210        220        230        240 
DKFKKWCDDY FFLAHRKEPR GIGGIFYDWL ESGDWDADFA FTQDVGRAFT AIYPELVRRN 

       250        260        270        280        290 
FEAPWQAADR EEQLIRRGRY VEFNLLYDRG TIFGLKTGGN VESILSSMPP EVKWP 

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References

[1]"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI05809.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001196 Genomic DNA. Translation: ACI94108.1.
CP002826 Genomic DNA. Translation: AEI05809.1.
RefSeqYP_002289973.1. NC_011386.1.
YP_004632050.1. NC_015684.1.

3D structure databases

ProteinModelPortalB6JI64.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6JI64.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10846222.
6992480.
GenomeReviewsGene locus OCAR_7000 in contig CP001196_GR.
KEGGoca:OCAR_7000.
PATRIC22807801. VBIOliCar134280_2848.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG631180.
OMAVKAYLLD.
ProtClustDBPRK05330.

Family and domain databases

HAMAPMF_00333. Coprogen_oxidas.
[Tree]
InterProIPR001260. Coprogen_oxidase_aer.
IPR018375. Coprogen_oxidase_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KOK00228.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
SUPFAMSSF102886. Coprogen_oxidas. 1 hit.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6JI64_OLICO
AccessionPrimary (citable) accession number: B6JI64
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)