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B6JH85

- LFTR_OLICO

UniProt

B6JH85 - LFTR_OLICO

Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
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    Functioni

    Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

    Catalytic activityi

    L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
    L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

    GO - Molecular functioni

    1. leucyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciOCAR504832:GJPZ-2049-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
    Alternative name(s):
    L/F-transferaseUniRule annotation
    LeucyltransferaseUniRule annotation
    PhenyalanyltransferaseUniRule annotation
    Gene namesi
    Name:aatUniRule annotation
    Ordered Locus Names:OCAR_5974, OCA5_c20490
    OrganismiOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)
    Taxonomic identifieri504832 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha
    ProteomesiUP000001678: Chromosome, UP000007730: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 227227Leucyl/phenylalanyl-tRNA--protein transferasePRO_1000131933Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi504832.OCAR_5974.

    Structurei

    3D structure databases

    ProteinModelPortaliB6JH85.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the L/F-transferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2360.
    HOGENOMiHOG000102326.
    KOiK00684.
    OMAiIGHAHSV.
    OrthoDBiEOG6WX4R3.

    Family and domain databases

    HAMAPiMF_00688. Leu_Phe_trans.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view]
    PfamiPF03588. Leu_Phe_trans. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 1 hit.
    TIGRFAMsiTIGR00667. aat. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B6JH85-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSRDSAASE ITPEVLLRAY ACGIFPMAES ADDPGLFWVE PEQRGIFPLE    50
    ALRISSRLAR TVRSDRYRIT IDTAFERVLG ECAAPAPGRE DTWINNRIRK 100
    LYSGLFEIGH CHSIEAWDGD DLAGGLYGVS LGGAFFGESM FHRSRDTSKV 150
    ALVHLAARLI IGGFTLLDTQ FVTDHLRSLG ATEVPRRKYR ALLDRALQLP 200
    GDFFALPADR PVSGADVLAI VRGTTAT 227
    Length:227
    Mass (Da):24,911
    Last modified:December 16, 2008 - v1
    Checksum:i84F1CE4E534FFCCA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001196 Genomic DNA. Translation: ACI93094.1.
    CP002826 Genomic DNA. Translation: AEI06756.1.
    RefSeqiYP_002288960.1. NC_011386.1.
    YP_004632997.1. NC_015684.1.

    Genome annotation databases

    EnsemblBacteriaiACI93094; ACI93094; OCAR_5974.
    AEI06756; AEI06756; OCA5_c20490.
    GeneIDi10847181.
    6992114.
    KEGGioca:OCAR_5974.
    ocg:OCA5_c20490.
    PATRICi22805831. VBIOliCar134280_1873.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001196 Genomic DNA. Translation: ACI93094.1 .
    CP002826 Genomic DNA. Translation: AEI06756.1 .
    RefSeqi YP_002288960.1. NC_011386.1.
    YP_004632997.1. NC_015684.1.

    3D structure databases

    ProteinModelPortali B6JH85.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 504832.OCAR_5974.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI93094 ; ACI93094 ; OCAR_5974 .
    AEI06756 ; AEI06756 ; OCA5_c20490 .
    GeneIDi 10847181.
    6992114.
    KEGGi oca:OCAR_5974.
    ocg:OCA5_c20490.
    PATRICi 22805831. VBIOliCar134280_1873.

    Phylogenomic databases

    eggNOGi COG2360.
    HOGENOMi HOG000102326.
    KOi K00684.
    OMAi IGHAHSV.
    OrthoDBi EOG6WX4R3.

    Enzyme and pathway databases

    BioCyci OCAR504832:GJPZ-2049-MONOMER.

    Family and domain databases

    HAMAPi MF_00688. Leu_Phe_trans.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view ]
    Pfami PF03588. Leu_Phe_trans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 1 hit.
    TIGRFAMsi TIGR00667. aat. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
      Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
      J. Bacteriol. 190:5531-5532(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49405 / DSM 1227 / OM5.
    2. "Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
      Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
      J. Bacteriol. 193:5043-5043(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49405 / DSM 1227 / OM5.

    Entry informationi

    Entry nameiLFTR_OLICO
    AccessioniPrimary (citable) accession number: B6JH85
    Secondary accession number(s): F8BW45
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3