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B6JFY3 (B6JFY3_OLICO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818

EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818 EMBL ACI93406.1
Ordered Locus Names:OCA5_c17410 EMBL AEI06455.1, OCAR_6293
OrganismOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]
Taxonomic identifier504832 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha

Protein attributes

Sequence length158 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. SAAS SAAS016856 HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. SAAS SAAS016856 HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. SAAS SAAS016856 HAMAP MF_00818

Subcellular location

Cytoplasm By similarity SAAS SAAS016856 HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
B6JFY3 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: F19C09425CB464BF

FASTA15817,721
        10         20         30         40         50         60 
MSRKPRPAAT KAPLQLGRPV TLPASPEEAK LDRVPNPHAG TDYLVRFAAP EFTSLCPITG 

        70         80         90        100        110        120 
QPDFAHLVID YVPGNWLVES KALKLYLASF RNHGAFHEDC TVAIGQRLVR EIKPRWLRIG 

       130        140        150 
GYWYPRGGIP IDVFWQSGRL PKNVWVPDQG VPPYRGRG 

« Hide

References

[1]"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI06455.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001196 Genomic DNA. Translation: ACI93406.1.
CP002826 Genomic DNA. Translation: AEI06455.1.
RefSeqYP_002289271.1. NC_011386.1.
YP_004632696.1. NC_015684.1.

3D structure databases

ProteinModelPortalB6JFY3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6JFY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10846873.
6990019.
GenomeReviewsGene locus OCAR_6293 in contig CP001196_GR.
KEGGoca:OCAR_6293.
PATRIC22806429. VBIOliCar134280_2165.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAHEDCTVA.
ProtClustDBPRK13258.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB6JFY3_OLICO
AccessionPrimary (citable) accession number: B6JFY3
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)