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B6JEN3 (B6JEN3_OLICO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 2 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 2 HAMAP MF_00223
Gene names
Name:folE EMBL ACI92755.1
Synonyms:folE2 HAMAP MF_00223 EMBL AEI07074.1
Ordered Locus Names:OCA5_c23780 EMBL AEI07074.1, OCAR_5624
OrganismOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]
Taxonomic identifier504832 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. SAAS SAAS001474 HAMAP MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. SAAS SAAS001474 HAMAP MF_00223

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
B6JEN3 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: 7598D7329C675305

FASTA22725,351
        10         20         30         40         50         60 
MDAVIKPLRS KLDKTEVPAA EIDQAGVRPD QPRPTREEAE SAVKTLLSYI GENPSREGLL 

        70         80         90        100        110        120 
DTPRRMVEAY DELFQGYHQC PAEVLNRTFG ETAGYDDFVL IRDIEFHSHC EHHVMPFYGK 

       130        140        150        160        170        180 
AHIAYTPVDR VVGLSKIARL VDAFAHRLQT QEHLTAQIAA ALDKVLQPRG VAVLLEAEHT 

       190        200        210        220 
CMSVRGIAKH GAKTVTSRFT GMFYDNPDEQ NRFLHMVRGI SAPFAGA

« Hide

References

[1]"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI07074.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001196 Genomic DNA. Translation: ACI92755.1.
CP002826 Genomic DNA. Translation: AEI07074.1.
RefSeqYP_002288620.1. NC_011386.1.
YP_004633315.1. NC_015684.1.

3D structure databases

ProteinModelPortalB6JEN3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6JEN3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10847510.
6991772.
GenomeReviewsGene locus OCAR_5624 in contig CP001196_GR.
KEGGoca:OCAR_5624.
PATRIC22805155. VBIOliCar134280_1546.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG370191.
OMACEAKHLC.
ProtClustDBPRK09347.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6JEN3_OLICO
AccessionPrimary (citable) accession number: B6JEN3
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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