B6JE29 (FCTA_OLICO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Formyl-coenzyme A transferase
Short name=Formyl-CoA transferase
EC=2.8.3.16

Gene names

Name:	frc
Ordered Locus Names:	OCAR_6550, OCA5_c15110

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]

Taxonomic identifier

504832 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha

Protein attributes

Sequence length	424 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate By similarity. HAMAP MF_00742
Catalytic activity	Formyl-CoA + oxalate = formate + oxalyl-CoA. HAMAP MF_00742
Pathway	Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2. HAMAP MF_00742
Sequence similarities	Belongs to the CaiB/BaiF CoA-transferase family.

Ontologies

Keywords
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	formyl-CoA transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 424	424	Formyl-coenzyme A transferase HAMAP MF_00742		PRO_1000189582
Sites
	Active site	168	1	Nucleophile By similarity
	Binding site	96	1	Coenzyme A By similarity

Sequences

	Sequence		Length	Mass (Da)
	B6JE29 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 01E771BC56F5F401	FASTA	424	46,189
	10 20 30 40 50 60 MAKALNGVRI LDFTHVQSGP TCTQLLAWFG ADVIKVERPG TGDITRGQLQ DVPNADSLYF 70 80 90 100 110 120 TMLNHNKRSI TLDAKNPKGK EVLTALIKSC DVMVENFAPG VLDRMGFSWE NIQKINPKLI 130 140 150 160 170 180 VASIKGFGPG PFEDCKVYEN VAQCTGGSAS TTGFRDGLPL VTGAQIGDSG TGLHLALGIV 190 200 210 220 230 240 TALFHRTHSG KGQRVTVAMQ DSVLNLCRVK MRDQQRLAHG PLKEYSQFGE GIPFGDATPR 250 260 270 280 290 300 AGNDSGGGQP GRILKCKGWE TDPNAYIYFI TQAAVWEKIC DVIGEPTWKT DPNYAKPGAR 310 320 330 340 350 360 LPRLNEIFGR IEQWTMTKTK FEVMNICNPF DIPCGPILSM KEIAEDKSLY ATGTLVEVDH 370 380 390 400 410 420 PTRGKYISVG NPIKLSDSPA DVRRSPLLGE HTDEILRDVL KFSESQVSDI RSSGALGEVP LAAE

References

[1]	"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T." Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L. J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5.
[2]	"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5." Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O. J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001196 Genomic DNA. Translation: ACI93662.1. CP002826 Genomic DNA. Translation: AEI06227.1.
RefSeq	YP_002289527.1. NC_011386.1. YP_004632468.1. NC_015684.1.
3D structure databases
ProteinModelPortal	B6JE29.
SMR	B6JE29. Positions 1-416.
ModBase	Search...
Protein-protein interaction databases
STRING	B6JE29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10846643. 6990518.
GenomeReviews	Gene locus OCAR_6550 in contig CP001196_GR.
KEGG	oca:OCAR_6550.
PATRIC	22806921. VBIOliCar134280_2410.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG659028.
OMA	QFGEGIP.
Family and domain databases
HAMAP	MF_00742. Formyl-CoA_transfer. [Tree]
InterPro	IPR003673. CoA-Trfase_fam_III. IPR023606. CoA-Trfase_III_dom. IPR017659. Formyl-CoA_transferase. [Graphical view]
Gene3D	G3DSA:3.40.50.10540. CoA-Trfase_fam_III. 1 hit.
KO	K07749.
PANTHER	PTHR11837. CAIB_BAIF. 1 hit.
Pfam	PF02515. CoA_transf_3. 1 hit. [Graphical view]
SUPFAM	SSF89796. CoA-Trfase_fam_III. 1 hit.
TIGRFAMs	TIGR03253. Oxalate_frc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FCTA_OLICO

Accession

Primary (citable) accession number: B6JE29
Secondary accession number(s): F8BYN2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	December 16, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program