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B6JDV0

- B6JDV0_OLICO

UniProt

B6JDV0 - B6JDV0_OLICO

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Protein

Adenylosuccinate lyase

Gene

purB

Organism
Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' AMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Purine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciOCAR504832:GJPZ-2525-MONOMER.
UniPathwayiUPA00074; UER00132.
UPA00075; UER00336.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
Short name:
ASLUniRule annotation
Alternative name(s):
AdenylosuccinaseUniRule annotation
Gene namesi
Name:purBImported
Ordered Locus Names:OCA5_c25250Imported, OCAR_5462Imported
OrganismiOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)Imported
Taxonomic identifieri504832 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha
ProteomesiUP000007730: Chromosome, UP000001678: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi504832.OCAR_5462.

Structurei

3D structure databases

ProteinModelPortaliB6JDV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0015.
HOGENOMiHOG000033912.
KOiK01756.
OMAiEMKYVWS.
OrthoDBiEOG686NDB.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SMARTiSM00998. ADSL_C. 1 hit.
[Graphical view]
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00928. purB. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6JDV0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPRYSRPEM TAIWEPQTRF QIWFEIEAHA ADALAEIGTI PKDAAKKVWE
60 70 80 90 100
KAKGVTFNVE RIDEIERETK HDVIAFLTHL AEIVGPEARF VHQGMTSSDV
110 120 130 140 150
LDTCLNVQLT RAADLLIADL DRVLAALKTR AFEHKLTPVI GRSHGIHAEP
160 170 180 190 200
VTFGLKLAYA YAEFTRARAR LVAARAEVAT CAISGAVGTF AQIDPRVEAH
210 220 230 240 250
VAKAMGLTVE PISTQVIPRD RHAMFFATLG VVAASMERLA IEIRHMQRTE
260 270 280 290 300
VLEAEEFFSQ GQKGSSAMPH KRNPVLTENL TGLSRMVRAY VTPALENVAL
310 320 330 340 350
WHERDISHSS AERMMGPDAT VTLDFALNRL AGVIEKLLVY PENMQKNLDR
360 370 380 390 400
LGGLVHSQRL LLALTQKGAS REDAYKLVQR NAMPVWRGEG DFQSLLKKDE
410 420 430
DVKKYLSDKE IEEQFDLAYH FKHVDTIFNR VFGAA
Length:435
Mass (Da):48,745
Last modified:December 16, 2008 - v1
Checksum:i825CD402A602EA1A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001196 Genomic DNA. Translation: ACI92594.1.
CP002826 Genomic DNA. Translation: AEI07220.1.
RefSeqiWP_012562623.1. NC_015684.1.
YP_002288459.1. NC_011386.1.
YP_004633461.1. NC_015684.1.

Genome annotation databases

EnsemblBacteriaiACI92594; ACI92594; OCAR_5462.
AEI07220; AEI07220; OCA5_c25250.
GeneIDi10847657.
6991449.
KEGGioca:OCAR_5462.
ocg:OCA5_c25250.
PATRICi22804843. VBIOliCar134280_1391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001196 Genomic DNA. Translation: ACI92594.1 .
CP002826 Genomic DNA. Translation: AEI07220.1 .
RefSeqi WP_012562623.1. NC_015684.1.
YP_002288459.1. NC_011386.1.
YP_004633461.1. NC_015684.1.

3D structure databases

ProteinModelPortali B6JDV0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 504832.OCAR_5462.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI92594 ; ACI92594 ; OCAR_5462 .
AEI07220 ; AEI07220 ; OCA5_c25250 .
GeneIDi 10847657.
6991449.
KEGGi oca:OCAR_5462.
ocg:OCA5_c25250.
PATRICi 22804843. VBIOliCar134280_1391.

Phylogenomic databases

eggNOGi COG0015.
HOGENOMi HOG000033912.
KOi K01756.
OMAi EMKYVWS.
OrthoDBi EOG686NDB.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00132 .
UPA00075 ; UER00336 .
BioCyci OCAR504832:GJPZ-2525-MONOMER.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
InterProi IPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SMARTi SM00998. ADSL_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00928. purB. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
    Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
    J. Bacteriol. 190:5531-5532(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49405 / DSM 1227 / OM5 and OM5Imported.
  2. "Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
    Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
    J. Bacteriol. 193:5043-5043(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49405 / DSM 1227 / OM5Imported, ATCC 49405 / DSM 1227 / OM5 [Mississippi]Imported and OM5Imported.

Entry informationi

Entry nameiB6JDV0_OLICO
AccessioniPrimary (citable) accession number: B6JDV0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3