B6JDD0 (ATP6_OLICO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase subunit a

Alternative name(s):
ATP synthase F0 sector subunit a
F-ATPase subunit 6

Gene names

Name:	atpB
Ordered Locus Names:	OCAR_4700, OCA5_c32500

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]

Taxonomic identifier

504832 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha › Oligotropha carboxidovorans

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity. HAMAP-Rule MF_01393
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01393.
Sequence similarities	Belongs to the ATPase A chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	ATP synthase subunit a HAMAP-Rule MF_01393		PRO_1000145295
Regions
	Transmembrane	30 – 50	21	Helical; Potential
	Transmembrane	84 – 104	21	Helical; Potential
	Transmembrane	114 – 134	21	Helical; Potential
	Transmembrane	143 – 163	21	Helical; Potential
	Transmembrane	193 – 213	21	Helical; Potential
	Transmembrane	220 – 240	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	B6JDD0 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 63A50E8E01E0A2D3	FASTA	249	26,977
	10 20 30 40 50 60 MADPVEQFEI HKIFSLGHIG GQEIAFTNSS LYMLLAVGAV ALLMLGGSAG RRLVPTRFQS 70 80 90 100 110 120 MAELSYEFVV NMVRESLGEE GMKFFPLVFS IFMFVLMANL IGVIPYTFSV TSHLIVTVAL 130 140 150 160 170 180 ALIVFLTVLL YGLYKNGLKF FRVFVPSGVP IYILPLIAMI EVISFLSRPV SHSVRLFANM 190 200 210 220 230 240 LAGHITLKVF ASFVTSLGAL GVAGIAGAAL PLAMTTAISI LEVLVALLQA YVFAILTCIY LNDALHPGH

References

[1]	"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T." Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L. J. Bacteriol. 190:5531-5532(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5.
[2]	"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5." Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O. J. Bacteriol. 193:5043-5043(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001196 Genomic DNA. Translation: ACI91842.1. CP002826 Genomic DNA. Translation: AEI07926.1.
RefSeq	YP_002287707.1. NC_011386.1. YP_004634167.1. NC_015684.1.
3D structure databases
ProteinModelPortal	B6JDD0.
ModBase	Search...
Protein-protein interaction databases
STRING	504832.OCAR_4700.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACI91842; ACI91842; OCAR_4700. AEI07926; AEI07926; OCA5_c32500.
GeneID	10848380. 6993450.
KEGG	oca:OCAR_4700. ocg:OCA5_c32500.
PATRIC	22803371. VBIOliCar134280_0668.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0356.
HOGENOM	HOG000253874.
KO	K02108.
OMA	FLPIPLM.
ProtClustDB	PRK05815.
Enzyme and pathway databases
BioCyc	OCAR504832:GJPZ-3248-MONOMER.
Family and domain databases
Gene3D	1.20.120.220. 1 hit.
HAMAP	MF_01393. ATP_synth_a_bact.
InterPro	IPR000568. ATPase_F0-cplx_asu. IPR023011. ATPase_F0-cplx_asu_AS. [Graphical view]
PANTHER	PTHR11410. PTHR11410. 1 hit.
Pfam	PF00119. ATP-synt_A. 1 hit. [Graphical view]
PRINTS	PR00123. ATPASEA.
SUPFAM	SSF81336. ATPase_F0_A. 1 hit.
TIGRFAMs	TIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITE	PS00449. ATPASE_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATP6_OLICO

Accession

Primary (citable) accession number: B6JDD0
Secondary accession number(s): F8BSJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	December 16, 2008
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program