B6JCU7 (B6JCU7_OLICO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898 EMBL ACI91677.1
Ordered Locus Names:	OCA5_c00050 EMBL AEI04739.1, OCAR_4532

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]

Taxonomic identifier

504832 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha

Protein attributes

Sequence length	812 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS002288 RuleBase RU003363 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. RuleBase RU000380 HAMAP MF_01898 Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 RuleBase RU000380 HAMAP MF_01898 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 RuleBase RU000380 HAMAP MF_01898
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B6JCU7 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: C6D994B7A53A261C	FASTA	812	89,402
	10 20 30 40 50 60 MSEPARLPTP DLTVAAAEYG AESIRVLKGL DAVRKRPGMY IGDTDDGSGL HHMVYEVVDN 70 80 90 100 110 120 AIDEALAGYA TRVEVILNPD GSVTVRDDGR GIPTDIHKGE GISAAEVIMT QLHAGGKFDQ 130 140 150 160 170 180 NSYKVSGGLH GVGVSVVNAL SSKLALRIWR GGKEHYIEFQ HGDAVAPLAV VGDAGGKRGT 190 200 210 220 230 240 EVTFHASPET FTHIEYDFDT LEHRLRELAF LNSGVNILLS DMRHAVERRE ELHYEGGVEA 250 260 270 280 290 300 FVKFLDRNKK AVVDKPIVMR AEQHGITVEV AMWWNDSYHE NVLCFTNNIP QRDGGTHLAG 310 320 330 340 350 360 FRGALTRQIT GYAEGMAKKE KIALTGDDCR EGLTAVLSVK VPDPKFSSQT KDKLVSSEVR 370 380 390 400 410 420 PVVESIINTA LSAWLEEHPT EARTIVGKVI EAAAAREAAR KARDLTRRKG ALDIASLPGK 430 440 450 460 470 480 LADCQERDPA KSELFIVEGD SAGGSAKQGR NREFQAVLPL RGKILNVERA RFDKMLSSEQ 490 500 510 520 530 540 IGTLITALGT GIGRDDFDLS KLRYHKIIVM TDADVDGAHI RTLLLTFFFR QMPQLIEAGH 550 560 570 580 590 600 LYIAQPPLYK VTRGKSEQYL KDERALEDYL IETGLDDCVL RLATGEERKG RDLQALVEDA 610 620 630 640 650 660 RTIRGLLANI HSRYNRSVVE QAAIAGVLNA RVTGNPETAR DAADYIAKRL DALADEVERG 670 680 690 700 710 720 WSGTFTEGQG FLFERTVRGV KEVATIDDAL LSSAEARRLD DFAAALQETF PRSAILRRKD 730 740 750 760 770 780 TETAIHGPVS LFEAVTEAGR KGVAYQRYKG LGEMNPEQLW ETTLDTNARS LLQVKIREVD 790 800 810 AADDIFTKLM GDIVEPRREF IQDNSLDANV DV

References

[1]	"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T." Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L. J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]	"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5." Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O. J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI04739.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001196 Genomic DNA. Translation: ACI91677.1. CP002826 Genomic DNA. Translation: AEI04739.1.
RefSeq	YP_002287542.1. NC_011386.1. YP_004630980.1. NC_015684.1.
3D structure databases
ProteinModelPortal	B6JCU7.
SMR	B6JCU7. Positions 24-391.
ModBase	Search...
Protein-protein interaction databases
STRING	B6JCU7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10845137. 6993285.
GenomeReviews	Gene locus OCAR_4532 in contig CP001196_GR.
KEGG	oca:OCAR_4532.
PATRIC	22803043. VBIOliCar134280_0507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B6JCU7_OLICO

Accession

Primary (citable) accession number: B6JCU7

Entry history

Integrated into UniProtKB/TrEMBL:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)