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B6JCH8 (B6JCH8_OLICO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Name:rdgB EMBL ACI91558.1
Ordered Locus Names:OCA5_c01190 EMBL AEI04851.1, OCAR_4412
OrganismOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]
Taxonomic identifier504832 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. SAAS SAAS020922 HAMAP MF_01405

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. SAAS SAAS020922 HAMAP MF_01405

Subunit structure

Homodimer By similarity. SAAS SAAS020922 HAMAP MF_01405

Sequence similarities

Belongs to the HAM1 NTPase family. RuleBase RU003781 HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B6JCH8 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: FDC3A6EF3C32261B

FASTA21222,825
        10         20         30         40         50         60 
MSNHRHITGR LVIATHNPGK LAEMRELLAP YGIEAVSAAE LNLDEPEETG TTFAANARIK 

        70         80         90        100        110        120 
ATAAANATGL PAFADDSGLC VDALEGQPGI YSARWAGPSK DFMAAMTQIE RLLQERDATE 

       130        140        150        160        170        180 
PAQRKAHFVS ALCVAWPDGH VEEVEERVDG QMVWPPRGTA GFGYDPAFLP DGHGRTFGEM 

       190        200        210 
TSIEKHGLPP HGMGLSHRAK AFVKLAEICL AR

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References

[1]"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI04851.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001196 Genomic DNA. Translation: ACI91558.1.
CP002826 Genomic DNA. Translation: AEI04851.1.
RefSeqYP_002287423.1. NC_011386.1.
YP_004631092.1. NC_015684.1.

3D structure databases

ProteinModelPortalB6JCH8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6JCH8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10845251.
6993166.
GenomeReviewsGene locus OCAR_4412 in contig CP001196_GR.
KEGGoca:OCAR_4412.
PATRIC22802803. VBIOliCar134280_0389.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAYSKRYDQ.
ProtClustDBPRK00120.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB6JCH8_OLICO
AccessionPrimary (citable) accession number: B6JCH8
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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