B6JC93 (B6JC93_OLICO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902 EMBL AEI07485.1
Ordered Locus Names:	OCA5_c27920 EMBL AEI07485.1, OCAR_5176

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]

Taxonomic identifier

504832 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha

Protein attributes

Sequence length	1107 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013 HAMAP MF_01902
Subcellular location	Cytoplasm By similarity SAAS SAAS004013 HAMAP MF_01902.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair SAAS SAAS004013 HAMAP MF_01902 DNA replication SAAS SAAS004013 HAMAP MF_01902
Cellular component	Cytoplasm SAAS SAAS004013 HAMAP MF_01902
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 HAMAP MF_01902 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B6JC93 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 0996EC9A928B411B	FASTA	1,107	125,370
	10 20 30 40 50 60 MTYAEIGITT NFSFLRGASH PQEYVHKASR YGLYAIGIAD RNTLAGVVRA YGELGNRNRK 70 80 90 100 110 120 VRYNPKLLIG TRLVFDDGTP DILAYPRDRE AYGRLCQLLS KGKLRGEKGE CHLRFDDLAE 130 140 150 160 170 180 FSEGQLLVVV SSYRFDSEKI LRVLGALKEL PAEGVWLAAT LFFHGDDRRR MLRLEHLAAK 190 200 210 220 230 240 THVSLIATND VLYHFHRRRA LQDVLSCIRE KVTIHEAGRR LEAHAERHLQ PHKEMARLYK 250 260 270 280 290 300 DFPDALEETI RFSDRITFSL DQLKYQYPDE PVPPGKTAQE HLRDLTETGI RKYFPEGIDE 310 320 330 340 350 360 GLRGTIEKEL RLIEKLGYAH YFLTVHDVVR YARSQHILCQ GRGSAANSAV CFMLGITSVN 370 380 390 400 410 420 PAETDVLFER FISEERLEPP DIDVDFEHSR REEVIQCVFQ RYGRHRAAIV ATVIDYRPRS 430 440 450 460 470 480 AIRDVGKALG LTEDVTAALA DTVWGSWGDS LSEMQVKQAG FDPTNPMIVR AVELATELIG 490 500 510 520 530 540 FPRHLSQHVG GFVLTQDRLD TYVPIGHAAM EDRTFIEWDK DDIDILKMMK VDVLALGMLT 550 560 570 580 590 600 CIRKCFDLIA DHKGRRYELA DVRSKDDDPV YKMLQRGESL GVFQVESRAQ MNMLPRLKPR 610 620 630 640 650 660 TFYDLVIEVA IVRPGPIQGN MVHPYLKRRN LKPEEIEYPY PKGGNPDELK SILHKTLGVP 670 680 690 700 710 720 LFQEQAMRIA MAAAEFTSEE ANGLRRAMAT FRHVGTMPKF EERMVGRMIK RGYDPKFAQS 730 740 750 760 770 780 CFDQIKGFGS YGFPESHAAA FAQLVYVSAW LKCFHPDAFA CGLLNSQPMG FYAPAQIVGD 790 800 810 820 830 840 ARTNGVDVRE IDVSFSFSQN TLEEKSGRHH ALRLGFRQID GFKCVDPDEQ EWRRRQGKDP 850 860 870 880 890 900 LEDWGRAIVE ARMQQPFASL EDFARETRLP KRALILLADA DAFRSLGLDR RSALWAVRRL 910 920 930 940 950 960 PDAVPLPLFQ SAAAREQPDE GSSPLPQMPL PEEVVADYQT VRLSLKGHPM EFLREMFEQE 970 980 990 1000 1010 1020 GVVPCAAVSH ENDKRRVRCA GVVLVRQRPG SANGVVFMTL EDETGIANIV VWPKVMATFR 1030 1040 1050 1060 1070 1080 KEVMGARLIE VEGVIQSSPD QVVHQLADRL VDRTSDLIGL ANDSLRPYQV ESAAGDGEGK 1090 1100 RLASLPSTAK ARHPREVRIL PASRDFH

References

[1]	"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T." Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L. J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]	"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5." Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O. J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI07485.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001196 Genomic DNA. Translation: ACI92309.1. CP002826 Genomic DNA. Translation: AEI07485.1.
RefSeq	YP_002288174.1. NC_011386.1. YP_004633726.1. NC_015684.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B6JC93.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10847924. 6991164.
GenomeReviews	Gene locus OCAR_5176 in contig CP001196_GR.
KEGG	oca:OCAR_5176.
PATRIC	22804291. VBIOliCar134280_1116.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B6JC93_OLICO

Accession

Primary (citable) accession number: B6JC93

Entry history

Integrated into UniProtKB/TrEMBL:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)