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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei149 – 1491UniRule annotation
Active sitei578 – 5781UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:OCAR_5313Imported
OrganismiOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5)Imported
Taxonomic identifieri504832 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha
ProteomesiUP000001678 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi504832.OCAR_5313.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6JBA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLDMTSERA DAQLRAEIRL LGRILGDTVR DHEGTDVFDL VESIRQASIR
60 70 80 90 100
FHRDEDVSAL HELEAMLNGR SIAETVRIVR AFSYFSHLAN IAEDQNHIRQ
110 120 130 140 150
TRNHSDAGLA TAATTLAGTV DRACDAGFSK EQLRDFFNDA LVSPVLTAHP
160 170 180 190 200
TEVRRKSTID REMEIAELLA DRDRTQMTSE ELAENDEQLR RCVATLWQTN
210 220 230 240 250
LLRRTKLTVL DEVQNGLSFY DYTFLKQLPR LINLLEDRLT PEDDDDDELA
260 270 280 290 300
SFLRMGSWIG GDRDGNPFVT ADVLRGTLQM QCERVMNFYI EELQQLYGEL
310 320 330 340 350
SLAVPLVKIS QELKTLCERS PDVSVHRDRE PYRRAVNGIY ARLKATARGL
360 370 380 390 400
DVDTVGRPVD EVDPYPNVEA FSDDLDIIHR SLVENGSRVI ARGRLRRLRR
410 420 430 440 450
AVDCFGFHLA SLDLRQNSAV HERTIAELFE VAASGTDYLS LSEEERCKLL
460 470 480 490 500
ARELKTVRPL ISPFVSYSEE TTSELDVLRA AAEAHAQFGR KVIRQSIVSM
510 520 530 540 550
AEGISDILEI AVLLKEAGLI DPNGRSHINL VPLFETIEDL RNCAGIMDRA
560 570 580 590 600
LSLPEYRRLV DSRGGLQEVM LGYSDSNKDG GFVTSGWELY KAEISLVDVF
610 620 630 640 650
AKQNVRLRLF HGRGGSVGRG GGPSYEAVLA QPGGAVNGQI RLTEQGEIIS
660 670 680 690 700
SKYSNPEVGR QNLEILAAAT LEASLLQPQH SAPREEYLAA MEELSALAFA
710 720 730 740 750
SYRGLVYETE GFEDYFWAST VINEISTLNI GSRPSSRSKA KRIENLRAIP
760 770 780 790 800
WVFSWAQCRL MLPGWYGFGS AVTEWLGKNP DKGLDFLREL YREWPFFRML
810 820 830 840 850
LSNMDMVLSK SSIAVASRYA DLVPDKTLRD TIFQRIRAEW QSSINWLLKI
860 870 880 890 900
MDQERLLGHN PLLERSIRHR FPYLDPLNHV QVEFLKAHRA KNEDPQVLRG
910
IQITINGISA GLRNSG
Length:916
Mass (Da):103,382
Last modified:December 15, 2008 - v1
Checksum:iD9096ACE591EBE0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001196 Genomic DNA. Translation: ACI92445.1.
RefSeqiWP_012562474.1. NC_011386.1.
YP_002288310.1. NC_011386.1.

Genome annotation databases

EnsemblBacteriaiACI92445; ACI92445; OCAR_5313.
KEGGioca:OCAR_5313.
PATRICi22804549. VBIOliCar134280_1244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001196 Genomic DNA. Translation: ACI92445.1.
RefSeqiWP_012562474.1. NC_011386.1.
YP_002288310.1. NC_011386.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi504832.OCAR_5313.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI92445; ACI92445; OCAR_5313.
KEGGioca:OCAR_5313.
PATRICi22804549. VBIOliCar134280_1244.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
    Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
    J. Bacteriol. 190:5531-5532(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi]Imported.

Entry informationi

Entry nameiB6JBA4_OLICO
AccessioniPrimary (citable) accession number: B6JBA4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2008
Last sequence update: December 15, 2008
Last modified: March 31, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.