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B6JAY7 (B6JAY7_OLICO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase RuleBase RU000607 HAMAP MF_00323

EC=4.99.1.1 RuleBase RU000607 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL ACI92061.1
Ordered Locus Names:OCA5_c30330 EMBL AEI07717.1, OCAR_4924
OrganismOligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP]
Taxonomic identifier504832 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeOligotropha

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. RuleBase RU004185 HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B6JAY7 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: D8F60C9DE9CE485F

FASTA34838,585
        10         20         30         40         50         60 
MDVAPETVLM SNSEPVLPQA AAGRVGVLLV NLGTPDTADA QGLRVYLREF LSDPRVIEDQ 

        70         80         90        100        110        120 
GLVWKLVLNG IILRVRPGKK AKDYLKIWNN ERNESPLKTI TRGQSDKLAA ALADNNVVVD 

       130        140        150        160        170        180 
WAMRYGNPSM QSGFDALMAK GCDRILVVPL YPQYSAATTA TVFDKAAEVM LALRAQPTLR 

       190        200        210        220        230        240 
FTPPYHVEPT YIEALAASVE AQLATLPFKP EVIVASFHGM PQKYVDKGDP YQAQCVATVE 

       250        260        270        280        290        300 
ALRERLKLSD KELILTFQSR FGYDPWLQPY TDETMKRLAG EGVKRIAVLT PGFSADCLET 

       310        320        330        340 
LEEIAQENAE IFRHAGGEQF SFIPCLNDSE GGMDVIRQLV LRELQGWI 

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References

[1]"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T."
Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L.
J. Bacteriol. 190:5531-5532(2008) [PubMed: 18539730] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi].
[2]"Complete genome sequences of the chemolithoautotrophic Oligotropha carboxidovorans strains OM4 and OM5."
Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O.
J. Bacteriol. 193:5043-5043(2011) [PubMed: 21742883] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI07717.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001196 Genomic DNA. Translation: ACI92061.1.
CP002826 Genomic DNA. Translation: AEI07717.1.
RefSeqYP_002287926.1. NC_011386.1.
YP_004633958.1. NC_015684.1.

3D structure databases

ProteinModelPortalB6JAY7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6JAY7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10848163.
6990915.
GenomeReviewsGene locus OCAR_4924 in contig CP001196_GR.
KEGGoca:OCAR_4924.
PATRIC22803811. VBIOliCar134280_0880.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMATIEEIGM.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6JAY7_OLICO
AccessionPrimary (citable) accession number: B6JAY7
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)