B6JAB7 (B6JAB7_OLICO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate kinase HAMAP-Rule MF_00109
Short name=SK HAMAP-Rule MF_00109
EC=2.7.1.71 HAMAP-Rule MF_00109

Gene names

Name:	aroK HAMAP-Rule MF_00109 EMBL ACI91227.1
Ordered Locus Names:	OCA5_c04330 EMBL AEI05158.1, OCAR_4076 EMBL ACI91227.1

Organism

Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) [Complete proteome] [HAMAP] EMBL ACI91227.1

Taxonomic identifier

504832 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Oligotropha › Oligotropha carboxidovorans

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP-Rule MF_00109
Catalytic activity	ATP + shikimate = ADP + shikimate 3-phosphate. SAAS SAAS000623 HAMAP-Rule MF_00109
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00109
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. SAAS SAAS000623 HAMAP-Rule MF_00109
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00109
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00109.
Sequence similarities	Belongs to the shikimate kinase family. HAMAP-Rule MF_00109

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS000623 HAMAP-Rule MF_00109
Cellular component	Cytoplasm HAMAP-Rule MF_00109
Ligand	ATP-binding SAAS SAAS023000 HAMAP-Rule MF_00109 Magnesium HAMAP-Rule MF_00109 Metal-binding HAMAP-Rule MF_00109 Nucleotide-binding
Molecular function	Kinase SAAS SAAS023000 HAMAP-Rule MF_00109 EMBL ACI91227.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP chorismate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP shikimate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	42 – 47	6	ATP By similarity HAMAP-Rule MF_00109
Sites
	Metal binding	46	1	Magnesium By similarity HAMAP-Rule MF_00109
	Binding site	64	1	Substrate By similarity HAMAP-Rule MF_00109
	Binding site	89	1	Substrate By similarity HAMAP-Rule MF_00109
	Binding site	111	1	Substrate; via amide nitrogen By similarity HAMAP-Rule MF_00109
	Binding site	149	1	ATP By similarity HAMAP-Rule MF_00109
	Binding site	168	1	Substrate By similarity HAMAP-Rule MF_00109

Sequences

	Sequence		Length	Mass (Da)
	B6JAB7 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 4B4F827226CB1953	FASTA	213	23,116
	10 20 30 40 50 60 MSPDEPAEMP ENLARQGVIQ NQTADILAAL GTRAIVLVGM MGSGKSTVGR RLAARLRLPF 70 80 90 100 110 120 VDADQEIETR HGGMTITEIF ATHGEPYFRE GEAKVISALL DGGAQVLATG GGAFVRDDTR 130 140 150 160 170 180 ERIRSKAVSI WLKADGATVL RRVKRRSDRP LLQTEDPAAT IERLIAAREP FYSLADLTIV 190 200 210 SRDVPHERIV DECIEALHGF LCAAAPVAFA NKT

References

[1]	"Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T." Paul D., Bridges S., Burgess S.C., Dandass Y., Lawrence M.L. J. Bacteriol. 190:5531-5532(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 [Mississippi] and OM5 EMBL ACI91227.1.
[2]	"Complete Genome Sequences of the Chemolithoautotrophic Oligotropha carboxidovorans Strains OM4 and OM5." Volland S., Rachinger M., Strittmatter A., Daniel R., Gottschalk G., Meyer O. J. Bacteriol. 193:5043-5043(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49405 / DSM 1227 / OM5 and OM5 EMBL AEI05158.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001196 Genomic DNA. Translation: ACI91227.1. CP002826 Genomic DNA. Translation: AEI05158.1.
RefSeq	YP_002287092.1. NC_011386.1. YP_004631399.1. NC_015684.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	504832.OCAR_4076.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACI91227; ACI91227; OCAR_4076. AEI05158; AEI05158; OCA5_c04330.
GeneID	10845565. 6991539.
KEGG	oca:OCAR_4076. ocg:OCA5_c04330.
PATRIC	22802161. VBIOliCar134280_0073.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0703.
HOGENOM	HOG000032568.
KO	K00891.
OMA	ADIPWIF.
Enzyme and pathway databases
BioCyc	OCAR504832:GJPZ-433-MONOMER.
UniPathway	UPA00053; UER00088.
Family and domain databases
HAMAP	MF_00109. Shikimate_kinase.
InterPro	IPR027417. P-loop_NTPase. IPR000623. Shikimate_kinase/TSH1. IPR023000. Shikimate_kinase_CS. [Graphical view]
Pfam	PF01202. SKI. 1 hit. [Graphical view]
PRINTS	PR01100. SHIKIMTKNASE.
SUPFAM	SSF52540. SSF52540. 1 hit.
PROSITE	PS01128. SHIKIMATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B6JAB7_OLICO

Accession

Primary (citable) accession number: B6JAB7

Entry history

Integrated into UniProtKB/TrEMBL:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	May 29, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)