Reviewed, UniProtKB/Swiss-Prot B6J8U0 (SYGA_COXB1)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	CbuK_0020

Organism

Coxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154)) [Complete proteome] [HAMAP]

Taxonomic identifier

434924 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000101178

Sequences

	Sequence		Length	Mass (Da)
	B6J8U0-1 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: FF52579A9F0787F8	FASTA	319	36,397
	10 20 30 40 50 60 MKSSHPVNFQ QMILALQEYW ASQGCVLLQP FDMEVGAGTF HPATFLRAIG PEPWRAAYVQ 70 80 90 100 110 120 PSRRPTDGRY GDNPNRTQHY YQFQVVLKPS PDDIQDIYLG SLKALGIDPL THDIRFVEDN 130 140 150 160 170 180 WEAPTLGSWG VGWEVWQDGM EITQFTYFQQ IGGLECKPVT GEITYGLERL AMFLQGIDNM 190 200 210 220 230 240 FDLVWTEGPN GRVTYGQIFQ QNEVEMSAYN FEYANVEALF NFFDFYEKEA SQLIEVHLPL 250 260 270 280 290 300 AAYEMVLKAS HTFNLLDARQ AISVTERQRF ILRVRKLAQA VAEAYYSARE KLGFPMLEEI 310 SSSSSRVLPL AGNDRVKGC

References

[1]

"Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella." Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A. Infect. Immun. 77:642-656(2009) [PubMed: 19047403] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001020 Genomic DNA. Translation: ACJ19348.1.
RefSeq	YP_002304493.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7014534.
GenomeReviews	Gene locus CbuK_0020 in contig CP001020_GR.
KEGG	cbc:CbuK_0020.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_COXB1

Accession

Primary (citable) accession number: B6J8U0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	December 16, 2008
Last modified:	June 16, 2009
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)