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B6J6S3

- G6PI_COXB1

UniProt

B6J6S3 - G6PI_COXB1

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Coxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei382 – 3821UniRule annotation
Active sitei509 – 5091UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBUR434924:GHWU-714-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:CbuK_0716
OrganismiCoxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154))
Taxonomic identifieri434924 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002504: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 547547Glucose-6-phosphate isomerasePRO_1000125711Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi434924.CbuK_0716.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6J6S3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLVESPPWQ ALKSKYQELS SLHMRDFFAQ DKKRGTRLSL EAAGLYFDYS
60 70 80 90 100
KNRVDEKTID LLCESANACN LPLRIEQLFS GKLTNESGEM VGFHTALRQV
110 120 130 140 150
NNFSFKTNNN AIQEIHASWE KIKKLSIRIR EGDYKGFTNK SITDIVNIGI
160 170 180 190 200
GGSSLGPQMA YNALKPYVKA PLRCHFISNL DDTDFYETVR TLNPETTLFI
210 220 230 240 250
ITSKTFTTKE TLENERRATE WLMQAAKKEN LIQTHFMAVT AAPEKAHEFG
260 270 280 290 300
IQKDNIFMLW PWVGGRFSVW SAAGLSLAIA IGWEEFFEFL RGAHAMDTHF
310 320 330 340 350
RQAEFNKNMP ILLALLSIWY INFFHAKTQA IIPYSQRLVY LPDYLTQLHM
360 370 380 390 400
ESLGKSVQLD GSAVHWQTGA VVWGDLGTNS QHSFHQLFLQ GTMVIPVDFI
410 420 430 440 450
AVLKNSRESH WQLPLIANCL GQSQTLMEGY DKEGVMRDLI NQGIEHEKAE
460 470 480 490 500
KLATYRLIRG NNPSNTIILE ELNPYSLGSL LALYEHKVYV QSVIWNINPF
510 520 530 540
DQWGVERGKH LAKDILQALQ AETDQSSFDS STERLINYVL KIKGNRP
Length:547
Mass (Da):62,385
Last modified:December 16, 2008 - v1
Checksum:i1E3C697BF59D80CD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001020 Genomic DNA. Translation: ACJ19972.1.
RefSeqiYP_002305117.1. NC_011528.1.

Genome annotation databases

EnsemblBacteriaiACJ19972; ACJ19972; CbuK_0716.
GeneIDi7015229.
KEGGicbc:CbuK_0716.
PATRICi17916845. VBICoxBur77120_0731.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001020 Genomic DNA. Translation: ACJ19972.1 .
RefSeqi YP_002305117.1. NC_011528.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 434924.CbuK_0716.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACJ19972 ; ACJ19972 ; CbuK_0716 .
GeneIDi 7015229.
KEGGi cbc:CbuK_0716.
PATRICi 17916845. VBICoxBur77120_0731.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CBUR434924:GHWU-714-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella."
    Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A.
    Infect. Immun. 77:642-656(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CbuK_Q154.

Entry informationi

Entry nameiG6PI_COXB1
AccessioniPrimary (citable) accession number: B6J6S3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 16, 2008
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3