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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Coxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:CbuK_2037
OrganismiCoxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154))
Taxonomic identifieri434924 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000993191 – 291Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST291

Proteomic databases

PRIDEiB6J646

Structurei

3D structure databases

ProteinModelPortaliB6J646
SMRiB6J646
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

B6J646-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDARAINSRE KADLKYPRNT YIIGDVQGCY RELQELLELI QFDSTKDRLG
60 70 80 90 100
FVGDLVNRGP NSLEVLRFLK SLSSPLIVLG NHDLYLLILG YGLMPEDSYE
110 120 130 140 150
HTLHAVLQAP DKLELLEWLR HCPLIRYEKS LSAVLVHAGL PPQWNIKESI
160 170 180 190 200
LHAEEISTAL KGPHYLAFLK NLFGNEPSQW KEDLEGQDRL RYICNAFTRM
210 220 230 240 250
RFCDAKGHLD LESEGKTNQA PSRFRPWFEW RNPQEDNVDI VFGHWAALNG
260 270 280 290
QSSAPHTHAL DTGCAWGYKL TGINLKTKER FSVPCQSALR M
Length:291
Mass (Da):33,302
Last modified:December 16, 2008 - v1
Checksum:i3A44DE9A327CC770
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001020 Genomic DNA Translation: ACJ21137.1
RefSeqiWP_005769711.1, NC_011528.1

Genome annotation databases

EnsemblBacteriaiACJ21137; ACJ21137; CbuK_2037
KEGGicbc:CbuK_2037

Similar proteinsi

Entry informationi

Entry nameiAPAH_COXB1
AccessioniPrimary (citable) accession number: B6J646
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: December 16, 2008
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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