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Protein
Submitted name:

ATP-dependent DNA ligase

Gene

CbuG_0044

Organism
Coxiella burnetii (strain CbuG_Q212) (Coxiella burnetii (strain Q212))
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC
  3. DNA primase activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciCBUR434923:GC8S-44-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligaseImported (EC:6.5.1.1Imported)
Gene namesi
Ordered Locus Names:CbuG_0044Imported
OrganismiCoxiella burnetii (strain CbuG_Q212) (Coxiella burnetii (strain Q212))Imported
Taxonomic identifieri434923 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000007729: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi434923.CbuG_0044.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR002755. DNA_primase_S.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6J2C9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILLSLKHYR QKRDFTKTSE PQGESASSSQ QFIYVIQKHD ASHLHYDLRL
60 70 80 90 100
ELDGVLKSWA VPKGPSLNSD LKRLAVEVED HPIDYATFEG NIPKGQYGAG
110 120 130 140 150
PVIVWDKGTW QPEGNAKENL KKGKLVFIIN GEKLKGKWAL VRLKTDDSKN
160 170 180 190 200
NWLLIKKKDH YATERFDIDN YPLSVISGAS IEEIKNHKLA LSLSDLKNAK
210 220 230 240 250
KTVVPEFIQP QLAKLKTVVP DSPDWIHEIK FDGYRIICII KKGIIQLMTR
260 270 280 290 300
NQKNWTEKLA GLAETMKSIP IDESILDGEI VVFDESGKTD FQLLQNAIKA
310 320 330 340 350
KKYNEIKYYL FDIPFCQKFD LSQVPLIMRK RLLKKLILQW KEKSGSILYS
360 370 380 390 400
SHIKGNGKAI LERACELGLE GIISKKIDAA YEQRRSSSWI KLKCKRQQEF
410 420 430 440 450
VIGGYTKPRG EQLYFGALLL GYYQNKKLIY CGRVGTGFSS LSLKDIYEKL
460 470 480 490 500
INREQKAPAF SELPPFGIKA GNHWVKPELV AEIEFAEWTK DKRLRQPVFK
510 520 530 540 550
GLREDKEAKG VKLETVKKTT VKNKSNNIKL TNPEKILYPE EKITKRQLAD
560 570 580 590 600
FYSKIADRLL PHIVHRPLML LRCPNGYNKE CFFQKHPDQN GEEFVYSVEI
610 620 630 640 650
EEKERKRYLT IHDEKGLLAL VQMGVLEIHP WGSSDSHPEK PDRLIFDIDP
660 670 680 690 700
HPAVSWKAVI NCATDVFEVL KALGLRSFVK TSGGKGLHVY VPIQPQLGWE
710 720 730 740 750
KLHEFAQKLA KLIVQVNPRL YTAELSKGKR LNKIFIDYIR NNRGATCVAP
760 770 780 790 800
YSTRAKKHVP LSTPVSWDEL SAVKSPTQFT IKNIFHRLEA LNQDPWEEFF
810
DIKQSITASM WKFFS
Length:815
Mass (Da):93,618
Last modified:December 16, 2008 - v1
Checksum:i493924B0FE189900
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001019 Genomic DNA. Translation: ACJ17503.1.
RefSeqiYP_002302648.1. NC_011527.1.

Genome annotation databases

EnsemblBacteriaiACJ17503; ACJ17503; CbuG_0044.
GeneIDi7012461.
KEGGicbg:CbuG_0044.
PATRICi17911087. VBICoxBur10955_0040.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001019 Genomic DNA. Translation: ACJ17503.1.
RefSeqiYP_002302648.1. NC_011527.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi434923.CbuG_0044.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACJ17503; ACJ17503; CbuG_0044.
GeneIDi7012461.
KEGGicbg:CbuG_0044.
PATRICi17911087. VBICoxBur10955_0040.

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Enzyme and pathway databases

BioCyciCBUR434923:GC8S-44-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR002755. DNA_primase_S.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella."
    Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A.
    Infect. Immun. 77:642-656(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CbuG_Q212Imported.

Entry informationi

Entry nameiB6J2C9_COXB2
AccessioniPrimary (citable) accession number: B6J2C9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: February 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.