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B6J0D6 (B6J0D6_COXB2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186
Ordered Locus Names:CbuG_1073
OrganismCoxiella burnetii (strain CbuG_Q212) (Coxiella burnetii (strain Q212)) [Complete proteome] [HAMAP] EMBL ACJ18414.1
Taxonomic identifier434923 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length514 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding422 – 4265ATP By similarity HAMAP MF_00186

Sites

Binding site251Substrate By similarity HAMAP MF_00186
Binding site291ATP By similarity HAMAP MF_00186
Binding site951Substrate By similarity HAMAP MF_00186
Binding site1481Substrate By similarity HAMAP MF_00186
Binding site2571Substrate By similarity HAMAP MF_00186
Binding site2791ATP By similarity HAMAP MF_00186
Binding site3221ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
B6J0D6 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: A2B91474BAA6FD64

FASTA51456,730
        10         20         30         40         50         60 
MKTGTHLLKF RGLMSSFILA IDQGTTSTRA ILFNEEAKLV HYHHVGITQY FPQGGWVEHD 

        70         80         90        100        110        120 
PEEIWDSTLL CCRNVLEEAS LRAADIAALG ISNQRETTIL WDRHTGQPLY RAIGWQDRRT 

       130        140        150        160        170        180 
VNFCEQLASQ AGVLAKFVEK TGLILDPYFS CSKIKWILDN IKGAYEKAKR GELAFGTVDS 

       190        200        210        220        230        240 
YLLWKFTGGK CHATDATNAS RTGLFNINQQ RWDDELLTLF DIPKSLLPTV LDNCAQFGFT 

       250        260        270        280        290        300 
DLDLLGHKIP ITAMIGDQQA AAVGQACIKP GMVKSTYGTG CFMLLNTGDQ IIHSRNRLLA 

       310        320        330        340        350        360 
TIAYRLNDTV TYGLEGSIFI AGAAVKWLRD PLHLIEKAND SESMASSVED TGGVYLVPAF 

       370        380        390        400        410        420 
TGLGAPYWDP NARGALFGLT RNTQREHIVR AALEAVCYQS KDLVRAILND GANLTTLRVD 

       430        440        450        460        470        480 
GGMAANNWLL QFLSDILGVN VDRSSCIESS ALGTAFLAGL GAGLFDSLEE MTGLWQADRH 

       490        500        510 
FIPQMDPKKR EELYDGWQKA VEKTLTPAAP LLFP

« Hide

References

[1]"Comparative genomics reveal extensive transposon-mediated genomic plasticity and diversity among potential effector proteins within the genus Coxiella."
Beare P.A., Unsworth N., Andoh M., Voth D.E., Omsland A., Gilk S.D., Williams K.P., Sobral B.W., Kupko J.J. III, Porcella S.F., Samuel J.E., Heinzen R.A.
Infect. Immun. 77:642-656(2009) [PubMed: 19047403] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001019 Genomic DNA. Translation: ACJ18414.1.
RefSeqYP_002303559.1. NC_011527.1.

3D structure databases

ProteinModelPortalB6J0D6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6J0D6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7013489.
GenomeReviewsGene locus CbuG_1073 in contig CP001019_GR.
KEGGcbg:CbuG_1073.
PATRIC17913200. VBICoxBur10955_1070.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG511469.
OMACYQTRDL.
ProtClustDBCLSK914422.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6J0D6_COXB2
AccessionPrimary (citable) accession number: B6J0D6
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info