Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene

gcvPA

Organism
Rhodospirillum centenum (strain ATCC 51521 / SW)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N6-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N6-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciRCEN414684:G1G8I-3511-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotation (EC:1.4.4.2UniRule annotation)
Alternative name(s):
Glycine cleavage system P-protein subunit 1UniRule annotation
Glycine decarboxylase subunit 1UniRule annotation
Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
Gene namesi
Name:gcvPAUniRule annotation
Ordered Locus Names:RC1_3658
OrganismiRhodospirillum centenum (strain ATCC 51521 / SW)
Taxonomic identifieri414684 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
Proteomesi
  • UP000001591 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001324871 – 449Probable glycine dehydrogenase (decarboxylating) subunit 1Add BLAST449

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotation

Protein-protein interaction databases

STRINGi414684.RC1_3658

Structurei

3D structure databases

ProteinModelPortaliB6IXI3
SMRiB6IXI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108EYQ Bacteria
COG0403 LUCA
HOGENOMiHOG000132025
KOiK00282
OMAiMYDGASA
OrthoDBiPOG091H0JKN

Family and domain databases

CDDicd00613 GDC-P, 1 hit
Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_00712 GcvPA, 1 hit
InterProiView protein in InterPro
IPR023010 GcvPA
IPR020581 GDC_P
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR42806 PTHR42806, 1 hit
PfamiView protein in Pfam
PF02347 GDC-P, 1 hit
PIRSFiPIRSF006815 GcvPA, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit

Sequencei

Sequence statusi: Complete.

B6IXI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYLPLTEAD RQAMLARIGV PDVDALFRDV PQAARLTAPI DGLPLHMGEL
60 70 80 90 100
EVDRLLSGMA AKNLTAGSVP SFLGAGAYRH HVPASVDQML LRGEFLTSYT
110 120 130 140 150
PYQPEVAQGT LQYLFEFQTQ VAEITGMEVA NASMYDGATG TAEAVLMATR
160 170 180 190 200
LTRRSKAVLS GGLHPHYREV VATTCGVLGM EVAAQAPDPT DAEDLLPLVD
210 220 230 240 250
DATACVVVQT PSLFGHPRDL SELAAACHAK GALLIAVVTE VVSLGLLTPP
260 270 280 290 300
GRMGADIVVC EGQSIGNPLN FGGPHVGLFA TREKFVRQMP GRLCGQTADA
310 320 330 340 350
EGKRGFVLTL STREQHIRRE KATSNICTNS GLCALAFTIH MALLGGEGFA
360 370 380 390 400
RLARLNHAKA VTLADRLAAV PGVEVLNGAF FNEFTLRLPR PAAPVVEALA
410 420 430 440
QRRILAGVPV SRLYPGEAGL ETLLLVAATE TNTEADMDAL VHGLQEVLR
Length:449
Mass (Da):47,725
Last modified:December 16, 2008 - v1
Checksum:i2FDBCB65D779E633
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000613 Genomic DNA Translation: ACJ01007.1
RefSeqiWP_012568783.1, NC_011420.2

Genome annotation databases

EnsemblBacteriaiACJ01007; ACJ01007; RC1_3658
KEGGirce:RC1_3658

Similar proteinsi

Entry informationi

Entry nameiGCSPA_RHOCS
AccessioniPrimary (citable) accession number: B6IXI3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 16, 2008
Last modified: April 25, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health