Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B6IU54

- SYL_RHOCS

UniProt

B6IU54 - SYL_RHOCS

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Rhodospirillum centenum (strain ATCC 51521 / SW)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei617 – 6171ATPUniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA editing activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRCEN414684:GHCM-2529-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
    Alternative name(s):
    Leucyl-tRNA synthetaseUniRule annotation
    Short name:
    LeuRSUniRule annotation
    Gene namesi
    Name:leuSUniRule annotation
    Ordered Locus Names:RC1_2551
    OrganismiRhodospirillum centenum (strain ATCC 51521 / SW)
    Taxonomic identifieri414684 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
    ProteomesiUP000001591: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 865865Leucine--tRNA ligasePRO_1000091352Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi414684.RC1_2551.

    Structurei

    3D structure databases

    ProteinModelPortaliB6IU54.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi41 – 5111"HIGH" regionAdd
    BLAST
    Motifi614 – 6185"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0495.
    HOGENOMiHOG000200747.
    KOiK01869.
    OMAiPVIHCPK.
    OrthoDBiEOG63Z74X.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 3 hits.
    3.90.740.10. 1 hit.
    HAMAPiMF_00049_B. Leu_tRNA_synth_B.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view]
    PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
    PfamiPF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 3 hits.
    PF13603. tRNA-synt_1_2. 1 hit.
    [Graphical view]
    PRINTSiPR00985. TRNASYNTHLEU.
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B6IU54-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSRYNVRETE AKWQAAWADA GSFAVTADPA KPKYYVLEMF PYPSGRIHMG    50
    HVRNYTMGDV VARFKRAKGF NVLHPMGWDA FGLPAENAAL EKGVHPGKWT 100
    YENIATMRGQ LQTMGLAIDW SREVATCRPE YYRHEQKIFL DFLKAGLAYR 150
    KESWVNWDPV DNTVLANEQV VDGRGWRTGA LVEKRKLSQW FLKITHFADD 200
    LLEALKGLER WPDKVRTMQE NWIGRSTGCR FFFRMSDGHP DLEVFTTRPD 250
    TLYGASFVAI SPNHPLAATL AAGNPALADF IAECNRTSTS EADIETAEKK 300
    GFATGVTAEH PFVPGWTLPV YVANFVLMEY GTGAIFGCPA HDQRDLDFAR 350
    KYGLPVKPVV IPEGQDPAAF AVADEAYTGP GVLRNSDFLD GLGVEEAKAA 400
    AIRRIEEAGR GQGTTMYRLR DWGVSRQRYW GCPIPVIHCP KCGAVPVPEA 450
    QLPVTLPDDV TFDAPGNPLA RHPTWKHVAC PCCGGAAERE TDTFDTFIES 500
    SWYFLRFADP RNGTLAFDPE LVKYWLPVDQ YIGGVEHAVL HLLYARFWTR 550
    ALAHCGYLDL AEPFAGLFTQ GMVTHATYQG TDGKWLFPAE VEFREGAMVK 600
    SDDGTAVTVG PIIKMSKSKK NVVDPQQIIE SYGADAARLF MMSDSPPDRD 650
    LEWTTAGIDG AWRYINRLWR LVTEPGFDLP APGTPAPASF GEEATAIRRL 700
    AHKAAQQIGE DIEGFRFNSS VARLRSFSNG VQDAFAKLAA KAAAGTAPAA 750
    DEAWAAREAL EMLARMVEPM MPHLAHEMWV ELGHAGLLLD RPWPAVDAAL 800
    VVEDTVTVAV QVNGKLRATI NLRRDAGNEE AQAAALADPA VQKAVEGKPL 850
    RKVVVVPNRI VNVVV 865
    Length:865
    Mass (Da):95,609
    Last modified:December 16, 2008 - v1
    Checksum:iE06C81181326B1AF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI99931.1.
    RefSeqiWP_012567713.1. NC_011420.2.
    YP_002298744.1. NC_011420.2.

    Genome annotation databases

    EnsemblBacteriaiACI99931; ACI99931; RC1_2551.
    GeneIDi7007319.
    KEGGirce:RC1_2551.
    PATRICi23320296. VBIRhoCen1465_2479.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI99931.1 .
    RefSeqi WP_012567713.1. NC_011420.2.
    YP_002298744.1. NC_011420.2.

    3D structure databases

    ProteinModelPortali B6IU54.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 414684.RC1_2551.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI99931 ; ACI99931 ; RC1_2551 .
    GeneIDi 7007319.
    KEGGi rce:RC1_2551.
    PATRICi 23320296. VBIRhoCen1465_2479.

    Phylogenomic databases

    eggNOGi COG0495.
    HOGENOMi HOG000200747.
    KOi K01869.
    OMAi PVIHCPK.
    OrthoDBi EOG63Z74X.

    Enzyme and pathway databases

    BioCyci RCEN414684:GHCM-2529-MONOMER.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 3 hits.
    3.90.740.10. 1 hit.
    HAMAPi MF_00049_B. Leu_tRNA_synth_B.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view ]
    PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
    Pfami PF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 3 hits.
    PF13603. tRNA-synt_1_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00985. TRNASYNTHLEU.
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rhodospirillum centenum."
      Touchman J.W., Bauer C., Blankenship R.E.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51521 / SW.

    Entry informationi

    Entry nameiSYL_RHOCS
    AccessioniPrimary (citable) accession number: B6IU54
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3