Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B6IST7

- LPXB_RHOCS

UniProt

B6IST7 - LPXB_RHOCS

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Rhodospirillum centenum (strain ATCC 51521 / SW)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciRCEN414684:GHCM-1176-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:RC1_1194
    OrganismiRhodospirillum centenum (strain ATCC 51521 / SW)
    Taxonomic identifieri414684 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
    ProteomesiUP000001591: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Lipid-A-disaccharide synthasePRO_1000205847Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi414684.RC1_1194.

    Structurei

    3D structure databases

    ProteinModelPortaliB6IST7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018004.
    KOiK00748.
    OMAiRRSEIRH.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B6IST7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKPLLIFLIA GEPSGDVLGG RLMAALREAM EGHVEFAGVG GPRMAEQGLQ    50
    SLFPMEDLAL FGLAELLPRL PTLLKRLDQT TKAVLERTPD AVVSIDAPDF 100
    CFRVEQRLRR AGARMPLIHY VAPTVWAWRP GRARKVAKFL DHLLALLPFE 150
    PPYFEAVGLP CTFVGHPVVE SGADAGDGER FRRRHGIAPD ATVLTVLPGS 200
    RRSEVTKLLP DFGATLEILA SRYPDLQVVV PTVPGVAETV AEAVQSWPVP 250
    AITLLGDADK YDAFAASTAA LAASGTVALE LALARVPAVI AYRIHPVSHA 300
    LYRRFIRVRY VNLVNIMLDR PLVPELLQQD CTPDRLALAV DRLLNEPSAR 350
    QEQIDGVTEV ARWLGQGDVP PSRRAAEAVL NVITKRVIAD RQGQTPGRSR 400
    S 401
    Length:401
    Mass (Da):43,713
    Last modified:December 16, 2008 - v1
    Checksum:iC25BE37E998BB01F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI98608.1.
    RefSeqiYP_002297421.1. NC_011420.2.

    Genome annotation databases

    EnsemblBacteriaiACI98608; ACI98608; RC1_1194.
    GeneIDi7005964.
    KEGGirce:RC1_1194.
    PATRICi23317596. VBIRhoCen1465_1149.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI98608.1 .
    RefSeqi YP_002297421.1. NC_011420.2.

    3D structure databases

    ProteinModelPortali B6IST7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 414684.RC1_1194.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI98608 ; ACI98608 ; RC1_1194 .
    GeneIDi 7005964.
    KEGGi rce:RC1_1194.
    PATRICi 23317596. VBIRhoCen1465_1149.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018004.
    KOi K00748.
    OMAi RRSEIRH.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci RCEN414684:GHCM-1176-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rhodospirillum centenum."
      Touchman J.W., Bauer C., Blankenship R.E.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51521 / SW.

    Entry informationi

    Entry nameiLPXB_RHOCS
    AccessioniPrimary (citable) accession number: B6IST7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3