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B6IST4

- SYE2_RHOCS

UniProt

B6IST4 - SYE2_RHOCS

Protein

Glutamate--tRNA ligase 2

Gene

gltX2

Organism
Rhodospirillum centenum (strain ATCC 51521 / SW)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

    Catalytic activityi

    ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei241 – 2411ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
    3. tRNA binding Source: InterPro

    GO - Biological processi

    1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRCEN414684:GHCM-1173-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate--tRNA ligase 2UniRule annotation (EC:6.1.1.17UniRule annotation)
    Alternative name(s):
    Glutamyl-tRNA synthetase 2UniRule annotation
    Short name:
    GluRS 2UniRule annotation
    Gene namesi
    Name:gltX2UniRule annotation
    Ordered Locus Names:RC1_1191
    OrganismiRhodospirillum centenum (strain ATCC 51521 / SW)
    Taxonomic identifieri414684 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
    ProteomesiUP000001591: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 468468Glutamate--tRNA ligase 2PRO_0000367750Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi414684.RC1_1191.

    Structurei

    3D structure databases

    ProteinModelPortaliB6IST4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi9 – 1911"HIGH" regionAdd
    BLAST
    Motifi238 – 2425"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0008.
    HOGENOMiHOG000252722.
    KOiK01885.
    OMAiHCLRASI.
    OrthoDBiEOG6DRPF7.

    Family and domain databases

    Gene3Di1.10.10.350. 1 hit.
    1.10.1160.10. 1 hit.
    3.40.50.620. 2 hits.
    HAMAPiMF_00022_B. Glu_tRNA_synth_B.
    InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
    IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
    IPR001412. aa-tRNA-synth_I_CS.
    IPR004527. Glu-tRNA-ligase_bac/mito.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 1 hit.
    [Graphical view]
    PRINTSiPR00987. TRNASYNTHGLU.
    SUPFAMiSSF48163. SSF48163. 1 hit.
    TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B6IST4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTIVTRFAPS PTGFLHIGGA RTALFNWLYA RGHGGKFLLR IEDTDRARST    50
    QAAVDAILDG LDWLGLEWDG DPISQFERKD RHAEVAHEML RRGMAYRCYA 100
    SPEELEAMKE EQRRQGLPMR YDGRWRDRDP SEAPAGVNPV IRLKAPQEGE 150
    TVVRDHVQGE VRVQNAQLDD MILLRSDGTP TYLLAVVVDD YDMGVTHVVR 200
    GDDHLTNTFR QLQIYAAMGW TPPEYAHVPL IHGPDGAKLS KRHGALGVDA 250
    YRDMGYLPET MRNYLLRLGW SHGDDEIIST DQAKAWFNLD DIGRSPSRLD 300
    FAKLDNLNGH YIRQSDDARL VSLVVPMVEK RLGRPLTGSE HARLLAAMPG 350
    FKPRVKTLVE LADGCLFLFA LRPLAMDDKA AALLTPEAKA QLGELHALFS 400
    GLGDWTGGAL EQAVRDFAER TGLKLGKVAQ PLRAALTGST VSPPIFEVAE 450
    VLGRTETLER IDDARKAG 468
    Length:468
    Mass (Da):52,030
    Last modified:December 16, 2008 - v1
    Checksum:i36817233D98A55D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI98605.1.
    RefSeqiYP_002297418.1. NC_011420.2.

    Genome annotation databases

    EnsemblBacteriaiACI98605; ACI98605; RC1_1191.
    GeneIDi7005961.
    KEGGirce:RC1_1191.
    PATRICi23317592. VBIRhoCen1465_1147.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000613 Genomic DNA. Translation: ACI98605.1 .
    RefSeqi YP_002297418.1. NC_011420.2.

    3D structure databases

    ProteinModelPortali B6IST4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 414684.RC1_1191.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI98605 ; ACI98605 ; RC1_1191 .
    GeneIDi 7005961.
    KEGGi rce:RC1_1191.
    PATRICi 23317592. VBIRhoCen1465_1147.

    Phylogenomic databases

    eggNOGi COG0008.
    HOGENOMi HOG000252722.
    KOi K01885.
    OMAi HCLRASI.
    OrthoDBi EOG6DRPF7.

    Enzyme and pathway databases

    BioCyci RCEN414684:GHCM-1173-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.350. 1 hit.
    1.10.1160.10. 1 hit.
    3.40.50.620. 2 hits.
    HAMAPi MF_00022_B. Glu_tRNA_synth_B.
    InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
    IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
    IPR001412. aa-tRNA-synth_I_CS.
    IPR004527. Glu-tRNA-ligase_bac/mito.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 1 hit.
    [Graphical view ]
    PRINTSi PR00987. TRNASYNTHGLU.
    SUPFAMi SSF48163. SSF48163. 1 hit.
    TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Rhodospirillum centenum."
      Touchman J.W., Bauer C., Blankenship R.E.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51521 / SW.

    Entry informationi

    Entry nameiSYE2_RHOCS
    AccessioniPrimary (citable) accession number: B6IST4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3