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B6IRF8 (B6IRF8_RHOCS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlB EMBL ACI98044.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:RC1_0609 EMBL ACI98044.1
OrganismRhodospirillum centenum (strain ATCC 51521 / SW) [Complete proteome] [HAMAP] EMBL ACI98044.1
Taxonomic identifier414684 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain112 – 309198ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding138 – 19154ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2591Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2761Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2761Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2781Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
B6IRF8 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: 9B0116EE14C958D5

FASTA31533,693
        10         20         30         40         50         60 
MGSGIMNQRR PTRVAVLMGG WSAERDVSLV SGRSVAAALE ERGYAVTAVD VQRDLPALLH 

        70         80         90        100        110        120 
ALTPKPDVVF NALHGRGGED GLIQGVLEYL GVPYTHSGVL ASALAMNKEM TRRVLAAVGV 

       130        140        150        160        170        180 
PVPDGVTVTR EQILAGHPIE PPYVVKPVDE GSSVGVRIVR PGQNQSVLEE GGWAYGERVL 

       190        200        210        220        230        240 
VERFIPGREL TVGVMGDRAL AVTEIVPRSG FFDYAAKYTE GEAVHVCPAQ IPQDVQEEAL 

       250        260        270        280        290        300 
RLALLAHRTL GCSGVSRSDF RWDDSQAGTG GLYFLETNTQ PGFTALSLLP EQAASQGIGF 

       310 
AELCAWIVEQ ARCHA 

« Hide

References

[1]"Genome sequence of Rhodospirillum centenum."
Touchman J.W., Bauer C., Blankenship R.E.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51521 / SW.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000613 Genomic DNA. Translation: ACI98044.1.
RefSeqYP_002296857.1. NC_011420.2.

3D structure databases

ProteinModelPortalB6IRF8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING414684.RC1_0609.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI98044; ACI98044; RC1_0609.
GeneID7005384.
KEGGrce:RC1_0609.
PATRIC23316432. VBIRhoCen1465_0577.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAKYTEGFA.
OrthoDBEOG6ND0KB.
ProtClustDBCLSK2804196.

Enzyme and pathway databases

BioCycRCEN414684:GHCM-596-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6IRF8_RHOCS
AccessionPrimary (citable) accession number: B6IRF8
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)