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Protein

Metallothionein

Gene

Mt2A

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals.UniRule annotation

GO - Molecular functioni

  • cadmium ion binding Source: RGD
  • drug binding Source: RGD
  • zinc ion binding Source: RGD

GO - Biological processi

Keywordsi

LigandMetal-binding, Metal-thiolate clusterUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
MetallothioneinUniRule annotation
Gene namesi
Name:Mt2AImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1592345. Mt2A.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSRNOG00000043098.
ExpressionAtlasiB6ID08. baseline.
GenevisibleiB6ID08. RN.

Structurei

3D structure databases

ProteinModelPortaliB6ID08.
SMRiB6ID08.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallothionein superfamily. Type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410JFS1. Eukaryota.
ENOG41113QR. LUCA.
HOVERGENiHBG096105.
KOiK14739.
OMAiCNCAGSC.
PhylomeDBiB6ID08.

Family and domain databases

Gene3Di4.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR003019. Metalthion.
IPR017854. Metalthion_dom_sf.
IPR023587. Metalthion_dom_vert.
IPR000006. Metalthion_vert.
IPR018064. Metalthion_vert_metal_BS.
PANTHERiPTHR23299. PTHR23299. 1 hit.
PfamiView protein in Pfam
PF00131. Metallothio. 1 hit.
PRINTSiPR00860. MTVERTEBRATE.
SUPFAMiSSF57868. SSF57868. 1 hit.
PROSITEiView protein in PROSITE
PS00203. METALLOTHIONEIN_VRT. 1 hit.

Sequencei

Sequence statusi: Complete.

B6ID08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPNCSCATD GSCSCAGSCK CKQCKCTSCK KSCCSCCPVG CAKCSQGCIC
60
KEASDKCSCC A
Length:61
Mass (Da):6,145
Last modified:December 16, 2008 - v1
Checksum:iD50D1306A5ED08E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC168768 mRNA. Translation: AAI68768.1.
RefSeqiNP_001131036.1. NM_001137564.1.
UniGeneiRn.115549.

Genome annotation databases

GeneIDi689415.
KEGGirno:689415.

Similar proteinsi

Entry informationi

Entry nameiB6ID08_RAT
AccessioniPrimary (citable) accession number: B6ID08
Entry historyiIntegrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: November 22, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)