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B6I6T9

- GLK_ECOSE

UniProt

B6I6T9 - GLK_ECOSE

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Protein

Glucokinase

Gene
glk, ECSE_2685
Organism
Escherichia coli (strain SE11)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL409438:GHUU-2726-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:ECSE_2685
OrganismiEscherichia coli (strain SE11)
Taxonomic identifieri409438 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000008199: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlucokinaseUniRule annotationPRO_1000127705Add
BLAST

Proteomic databases

PRIDEiB6I6T9.

Interactioni

Protein-protein interaction databases

STRINGi409438.ECSE_2685.

Structurei

3D structure databases

ProteinModelPortaliB6I6T9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDWVEMTN.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

B6I6T9-1 [UniParc]FASTAAdd to Basket

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MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVIRVYLE    50
EHKVEVKDGC IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND 100
FTAVSMAIPM LKKEHLIQFG GAEPVEGKPI AVYGAGTGLG VAHLVHVDKR 150
WVSLPGEGGH VDFAPNSEEE AIILEILRAE IGHVSAERVL SGPGLVNLYR 200
AIVKADNRLP ENLKPKDITE RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
NLGTFGGVFI AGGIVPRFLE FFKASGFRAA FEDKGRFKEY VHDIPVYLIV 300
HDNPGLLGSG AHLRQTLGHI L 321
Length:321
Mass (Da):34,723
Last modified:December 16, 2008 - v1
Checksum:i2D6CD956641A3823
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP009240 Genomic DNA. Translation: BAG78209.1.
RefSeqiYP_002293960.1. NC_011415.1.

Genome annotation databases

EnsemblBacteriaiBAG78209; BAG78209; ECSE_2685.
GeneIDi7001070.
KEGGiecy:ECSE_2685.
PATRICi18423930. VBIEscCol83070_2848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP009240 Genomic DNA. Translation: BAG78209.1 .
RefSeqi YP_002293960.1. NC_011415.1.

3D structure databases

ProteinModelPortali B6I6T9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 409438.ECSE_2685.

Proteomic databases

PRIDEi B6I6T9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAG78209 ; BAG78209 ; ECSE_2685 .
GeneIDi 7001070.
KEGGi ecy:ECSE_2685.
PATRICi 18423930. VBIEscCol83070_2848.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi DWVEMTN.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci ECOL409438:GHUU-2726-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult."
    Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T., Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.
    DNA Res. 15:375-386(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SE11.

Entry informationi

Entry nameiGLK_ECOSE
AccessioniPrimary (citable) accession number: B6I6T9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 16, 2008
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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