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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Pc22g22110

Organism
Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Enzyme and pathway databases

BioCyciPCHR:PC22G22110-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:Pc22g22110Imported, PCH_Pc22g22110Imported
OrganismiPenicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
ProteomesiUP000000724 Componenti: Contig Pc00c22

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi500485.B6HTR5.

Structurei

3D structure databases

ProteinModelPortaliB6HTR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
KOiK00006.
OMAiEVANDNF.
OrthoDBiEOG7V76H7.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

B6HTR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSVAPYQRK HKVTVVGSGN WGCAIAKIVA ENASFHPDLF EEKVEMWVFE
60 70 80 90 100
ENVEIPKTSK NYDASNPGPR KLTEVINNVH ENVKYLPGIQ LPVNLHANPS
110 120 130 140 150
LEDAVKDSTI LIFNLPHQFI IKTCEQLKGK ILPYARGISC IKGVDVNSTG
160 170 180 190 200
IHLFSETIGR ILGIYCGALS GANIANEVAQ EKWCETSIAY DPPHMDSQVP
210 220 230 240 250
TPQRSPSSST TNLVEFQHKD TSGQISEVKL QALPSEYPPV DHAVLKTLFH
260 270 280 290 300
RPYFHVRVVS DVAGVSISGA LKNIVALAAG YVVGLGWGDN AKAAIMRVGL
310 320 330 340 350
MEMVKFGDAF FSATIDTRTF TDESAGVADL ITSSSSGRNF RCAKLSVERN
360 370 380 390 400
QPIEEIEKTE LNGQKLQGTL TAMEVNSFLK NQGMEAEFPL FTAVFRILEG
410 420 430 440
TMKVEDIPSY IERPPQARAP TSAPQDSNED NGARFSAARL
Length:440
Mass (Da):48,121
Last modified:December 15, 2008 - v1
Checksum:i19DF8540C62282F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920437 Genomic DNA. Translation: CAP99499.1.
RefSeqiXP_002566106.1. XM_002566060.1.

Genome annotation databases

GeneIDi8308373.
KEGGipcs:Pc22g22110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920437 Genomic DNA. Translation: CAP99499.1.
RefSeqiXP_002566106.1. XM_002566060.1.

3D structure databases

ProteinModelPortaliB6HTR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi500485.B6HTR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8308373.
KEGGipcs:Pc22g22110.

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
KOiK00006.
OMAiEVANDNF.
OrthoDBiEOG7V76H7.

Enzyme and pathway databases

BioCyciPCHR:PC22G22110-MONOMER.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255Imported.

Entry informationi

Entry nameiB6HTR5_PENCW
AccessioniPrimary (citable) accession number: B6HTR5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2008
Last sequence update: December 15, 2008
Last modified: February 3, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.