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Protein

Superoxide dismutase

Gene

Pc22g04680

Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi59Divalent metal cationUniRule annotation1
Metal bindingi107Divalent metal cationUniRule annotation1
Metal bindingi193Divalent metal cationUniRule annotation1
Metal bindingi197Divalent metal cationUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPCHR:PC22G04680-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:Pc22g04680Imported, PCH_Pc22g04680Imported
OrganismiPenicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum species complex
Proteomesi
  • UP000000724 Componenti: Contig Pc00c22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi500485.XP_002564506.1

Structurei

3D structure databases

ProteinModelPortaliB6HTH1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 115Sod_Fe_NInterPro annotationAdd BLAST80
Domaini125 – 226Sod_Fe_CInterPro annotationAdd BLAST102

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0876 Eukaryota
COG0605 LUCA
HOGENOMiHOG000013583
KOiK04564
OMAiKWGSFDK
OrthoDBiEOG092C4NQ6

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

B6HTH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALLSNSAR VALRSGASAT SKAGAAGLTF ARGKATLPDL SYDYGALEPS
60 70 80 90 100
ISGKIMEVHH KNHHNTYVTS YNNTLEQLQE AQAKGDIATQ IALKPAVNFH
110 120 130 140 150
GGGHLNHTLF WENLAPKSAG GGEPPSGALS KAIDSTYGSL GEFQSKMNAA
160 170 180 190 200
LAGIQGSGWA WLVKDKQTGQ IGIRTYANQD PVVGQFQPLL GIDAWEHAYY
210 220
LQYQNRKAEY FSAIWDVINW KTVEKRFT
Length:228
Mass (Da):24,683
Last modified:December 16, 2008 - v1
Checksum:iE3D715EC38D8651D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920437 Genomic DNA Translation: CAP97756.1
RefSeqiXP_002564506.1, XM_002564460.1

Genome annotation databases

EnsemblFungiiCAP97756; CAP97756; PCH_Pc22g04680
GeneIDi8310888
KEGGipcs:Pc22g04680

Similar proteinsi

Entry informationi

Entry nameiB6HTH1_PENRW
AccessioniPrimary (citable) accession number: B6HTH1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health