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Protein

Glutamate decarboxylase

Gene

Pc22g00970

Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciPCHR:PC22G00970-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:Pc22g00970Imported, PCH_Pc22g00970Imported
OrganismiPenicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
Proteomesi
  • UP000000724 Componenti: Contig Pc00c22

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei292N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi500485.XP_002564142.1.

Structurei

3D structure databases

ProteinModelPortaliB6HPQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1383. Eukaryota.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiIDEYTIG.
OrthoDBiEOG092C1P0W.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B6HPQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLAKVKKD NEVPPSTHDI VSVAPPDIDD FETNVYGSHF AADHMPLHEM
60 70 80 90 100
PEREMPRQIA ARMIKDELSL DGNPKLNLAS FVTTYMEDEI EQIMTESFSK
110 120 130 140 150
NFIDYEEYPH SAEIQNRCVN MIARLFHIPT DASGENAMGT STIGSSEAIM
160 170 180 190 200
LGTLAMKKRW QNKRKAEGKD YSRPNIIMNS AVQVCWEKAA RYFEIEEKYV
210 220 230 240 250
YCTDTRFVID PKQAVDLVDE NTIGICAILG TTYTGEYEDI KAINDLLVER
260 270 280 290 300
NIDCPIHVDA ASGGFVAPFI QPDLKWDFRL EKVVSINVSG HKYGLVYPGV
310 320 330 340 350
GWVIWRSPEY LPQELVFNIN YLGADQASFT LNFSKGASHV IGQYYQLIRL
360 370 380 390 400
GKHGYRAIMS NITRISDYMS SEFEKMGMVI LSQTQGRGLP LVAWRLPTDD
410 420 430 440 450
SRIYDEFAVA HQLRERGWIV PAYTMAPNSE KLQMMRIVIR EDFSMHRCDS
460 470 480 490 500
LLQDFKLAIE SLDAMDKSML DKYKTHMKNH RNHPRHQSRV HAHYMNEKHS
510
LQGQTGKTHG VC
Length:512
Mass (Da):58,546
Last modified:December 16, 2008 - v1
Checksum:i8BE7B1FF18515D1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920437 Genomic DNA. Translation: CAP97385.1.
RefSeqiXP_002564142.1. XM_002564096.1.

Genome annotation databases

EnsemblFungiiCAP97385; CAP97385; PCH_Pc22g00970.
GeneIDi8306589.
KEGGipcs:Pc22g00970.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920437 Genomic DNA. Translation: CAP97385.1.
RefSeqiXP_002564142.1. XM_002564096.1.

3D structure databases

ProteinModelPortaliB6HPQ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi500485.XP_002564142.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAP97385; CAP97385; PCH_Pc22g00970.
GeneIDi8306589.
KEGGipcs:Pc22g00970.

Phylogenomic databases

eggNOGiKOG1383. Eukaryota.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiIDEYTIG.
OrthoDBiEOG092C1P0W.

Enzyme and pathway databases

BioCyciPCHR:PC22G00970-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB6HPQ4_PENRW
AccessioniPrimary (citable) accession number: B6HPQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: September 7, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.