ID   B6HP74_PENRW            Unreviewed;       407 AA.
AC   B6HP74;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Pc22g00140 protein {ECO:0000313|EMBL:CAP97302.1};
GN   ORFNames=Pc22g00140 {ECO:0000313|EMBL:CAP97302.1}, PCH_Pc22g00140
GN   {ECO:0000313|EMBL:CAP97302.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP97302.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP97302.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
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DR   EMBL; AM920437; CAP97302.1; -; Genomic_DNA.
DR   RefSeq; XP_002564062.1; XM_002564016.1.
DR   AlphaFoldDB; B6HP74; -.
DR   STRING; 500485.B6HP74; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   GeneID; 8303892; -.
DR   KEGG; pcs:Pc22g00140; -.
DR   VEuPathDB; FungiDB:PCH_Pc22g00140; -.
DR   eggNOG; ENOG502QSIT; Eukaryota.
DR   HOGENOM; CLU_024620_1_1_1; -.
DR   OMA; IRSYDAC; -.
DR   OrthoDB; 5482010at2759; -.
DR   BioCyc; PCHR:PC22G00140-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c22.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..407
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002843723"
FT   DOMAIN          83..380
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
FT   REGION          71..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          276..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..98
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  42706 MW;  30276E47B93A5335 CRC64;
     MLSSLMYLAR ECSILRAISL CAILAVATPA ASASVTAKHT LATNGKGLFP QYRIVALASL
     GNGVLLASYD GRPDGGDSPS PNSILQRRST DGGKTWGNPT YIARGQPASS TLQQYGFSDP
     SYVVDSGTGK VFNFHVFSKN QGFLNSEIGN DDTDLNIVSA EVSVSTDGGL SWTTDPDHES
     SLPPVASADV ANVGGITGMF ASSGEGIQLK YGKHAGRLVQ QFLGKVIQSD GSKVSQAYSV
     YSDDGGAIWK MGKVIGTGMD ENKVVELSNG NLMLNSRPSD GSGYRKVATS TDGGETWSTP
     ASETQLPDPG NNGAITRMYP DAAHGSANAK ILLFTNANSK TSRSNGTIRY SCDDGKTWSS
     GAVFQSGSMS YSTVTALGDD RFGIFYEGDS NDLVYIEVSK DFIGVSC
//