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B6HK40

- B6HK40_PENCW

UniProt

B6HK40 - B6HK40_PENCW

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Protein

DNA ligase

Gene
Pc21g07170, PCH_Pc21g07170
Organism
Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPCHR:PC21G07170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Pc21g07170Imported, PCH_Pc21g07170Imported
OrganismiPenicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
ProteomesiUP000000724: Contig Pc00c21

Interactioni

Protein-protein interaction databases

STRINGi500485.B6HK40.

Structurei

3D structure databases

ProteinModelPortaliB6HK40.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
KOiK10777.
OMAiHMCPSTK.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6HK40-1 [UniParc]FASTAAdd to Basket

« Hide

MDSDEILGQD DVLKPEQEED LDEKYPNRPH NRAPTLPFHD LYLDLFNPLS    50
ELKKKPSGPA PARRKAGPHG KGATSLNPFE RRRDVIERFI SRWRKDVGDD 100
IYPALRLILP DKDRDRPMYG IKEKAIGRML VKIMKINKES EDGYNLLNWK 150
LPGQGATTRM AGDFARRCFD VLSKRPMRTD PGDMTIEEVN EKLDKLSAAS 200
KEDEQLPILT EFYRRMNPEE LLWLIRIILR QMKVGATERT FFDVWHPDAE 250
NLYSISSSLR RVCWELHDPN IRLEGEERGI ALMQCFQPQL AQFQMHSFER 300
IIARMKPTED DNVFWIEEKM DGERMQLHMA PDDSTKGGRK FGFWSRKAKE 350
YTYLYGNGIY DENGALTRHL KDAFVDGVQS IILDGEMITW DPEQDAMVPF 400
GTLKTAALAE QRNPFSNGPR PLFRVFDILH LNGRDLTKYT LRDRRNALEK 450
TVRPVHRRFE IHSYEEATTT TEVEAALRKV VAEASEGLVL KNPRSPYRLN 500
ERHDDWMKVK PDYMTEFGES LDVIVIGGYY GSGRRGGALS SFLCGLRVDD 550
STQAAEKCWS FCKVGGGFTA ADYQEVRHHT DGKWKAWDAK KPPTTFVELA 600
GGDAQHERPD MWIKPSDSIV LCVKAASVAI SDQFRMGLAL RFPRFKKLRK 650
DKDWKTALSV QEFLDLKSNA EQEHREKEFS VDNSRKKRVK RATKKPLTVA 700
GHEDNVDVQY LGPSGHVFDE LNFFIMTEST VPEKKTKLQL EQLVKANGGK 750
IYQTKTAAVD TLCVAERRTV KVASLQKSGE QNIIRPSWLI DCVKQNEIDA 800
GLPDLLLPFE PRHMFFMTEE KEEEVAANVD KFMDSYARDT TVNELKDADD 850
VPDPETTQRI ETRIQERVNA GYTVPVGWLF RGLKFHFYSN GNQPDESASR 900
EIRREDQRLQ FARNTARFAA AEIAKTLKSS GITHVIVDPE TVSSADKTSL 950
RNTLAAKPGA KMPHLVSVGW VEECWKNGTL LDEERFPILR 990
Length:990
Mass (Da):113,516
Last modified:December 16, 2008 - v1
Checksum:i4ED51FADC197051E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM920436 Genomic DNA. Translation: CAP95614.1.
RefSeqiXP_002567758.1. XM_002567712.1.

Genome annotation databases

GeneIDi8314155.
KEGGipcs:Pc21g07170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM920436 Genomic DNA. Translation: CAP95614.1 .
RefSeqi XP_002567758.1. XM_002567712.1.

3D structure databases

ProteinModelPortali B6HK40.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 500485.B6HK40.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8314155.
KEGGi pcs:Pc21g07170.

Phylogenomic databases

eggNOGi COG1793.
KOi K10777.
OMAi HMCPSTK.
OrthoDBi EOG7QC84G.

Enzyme and pathway databases

BioCyci PCHR:PC21G07170-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255.

Entry informationi

Entry nameiB6HK40_PENCW
AccessioniPrimary (citable) accession number: B6HK40
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: December 11, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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