B6HK40 (B6HK40_PENCW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

Pc21g07170 EMBL CAP95614.1

Organism

Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum) [Complete proteome] EMBL CAP95614.1

Taxonomic identifier

500485 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Penicillium › Penicillium chrysogenum complex › Penicillium chrysogenum

Protein attributes

Sequence length	990 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B6HK40 [UniParc]. Last modified December 16, 2008. Version 1. Checksum: 4ED51FADC197051E	FASTA	990	113,516
	10 20 30 40 50 60 MDSDEILGQD DVLKPEQEED LDEKYPNRPH NRAPTLPFHD LYLDLFNPLS ELKKKPSGPA 70 80 90 100 110 120 PARRKAGPHG KGATSLNPFE RRRDVIERFI SRWRKDVGDD IYPALRLILP DKDRDRPMYG 130 140 150 160 170 180 IKEKAIGRML VKIMKINKES EDGYNLLNWK LPGQGATTRM AGDFARRCFD VLSKRPMRTD 190 200 210 220 230 240 PGDMTIEEVN EKLDKLSAAS KEDEQLPILT EFYRRMNPEE LLWLIRIILR QMKVGATERT 250 260 270 280 290 300 FFDVWHPDAE NLYSISSSLR RVCWELHDPN IRLEGEERGI ALMQCFQPQL AQFQMHSFER 310 320 330 340 350 360 IIARMKPTED DNVFWIEEKM DGERMQLHMA PDDSTKGGRK FGFWSRKAKE YTYLYGNGIY 370 380 390 400 410 420 DENGALTRHL KDAFVDGVQS IILDGEMITW DPEQDAMVPF GTLKTAALAE QRNPFSNGPR 430 440 450 460 470 480 PLFRVFDILH LNGRDLTKYT LRDRRNALEK TVRPVHRRFE IHSYEEATTT TEVEAALRKV 490 500 510 520 530 540 VAEASEGLVL KNPRSPYRLN ERHDDWMKVK PDYMTEFGES LDVIVIGGYY GSGRRGGALS 550 560 570 580 590 600 SFLCGLRVDD STQAAEKCWS FCKVGGGFTA ADYQEVRHHT DGKWKAWDAK KPPTTFVELA 610 620 630 640 650 660 GGDAQHERPD MWIKPSDSIV LCVKAASVAI SDQFRMGLAL RFPRFKKLRK DKDWKTALSV 670 680 690 700 710 720 QEFLDLKSNA EQEHREKEFS VDNSRKKRVK RATKKPLTVA GHEDNVDVQY LGPSGHVFDE 730 740 750 760 770 780 LNFFIMTEST VPEKKTKLQL EQLVKANGGK IYQTKTAAVD TLCVAERRTV KVASLQKSGE 790 800 810 820 830 840 QNIIRPSWLI DCVKQNEIDA GLPDLLLPFE PRHMFFMTEE KEEEVAANVD KFMDSYARDT 850 860 870 880 890 900 TVNELKDADD VPDPETTQRI ETRIQERVNA GYTVPVGWLF RGLKFHFYSN GNQPDESASR 910 920 930 940 950 960 EIRREDQRLQ FARNTARFAA AEIAKTLKSS GITHVIVDPE TVSSADKTSL RNTLAAKPGA 970 980 990 KMPHLVSVGW VEECWKNGTL LDEERFPILR

References

[1]

"Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum." van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.M., Driessen A.J., Garcia-Estrada C., Fedorova N.D., Harris D.M., Heijne W.H., Joardar V., Kiel J.A., Kovalchuk A., Martin J.F., Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A. , van der Klei I.J., van Peij N.N., Veenhuis M., von Dohren H., Wagner C., Wortman J., Bovenberg R.A. Nat. Biotechnol. 26:1161-1168(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM920436 Genomic DNA. Translation: CAP95614.1.
RefSeq	XP_002567758.1. XM_002567712.1.
3D structure databases
ProteinModelPortal	B6HK40.
ModBase	Search...
Protein-protein interaction databases
STRING	500485.B6HK40.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8314155.
KEGG	pcs:Pc21g07170.
Phylogenomic databases
eggNOG	COG1793.
KO	K10777.
OrthoDB	EOG41K2MD.
Enzyme and pathway databases
BioCyc	PCHR:PC21G07170-MONOMER.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit. 3.40.50.10190. 2 hits.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B6HK40_PENCW

Accession

Primary (citable) accession number: B6HK40

Entry history

Integrated into UniProtKB/TrEMBL:	December 16, 2008
Last sequence update:	December 16, 2008
Last modified:	May 29, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)