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B6HK40

- B6HK40_PENCW

UniProt

B6HK40 - B6HK40_PENCW

Protein

DNA ligase

Gene

Pc21g07170

Organism
Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (16 Dec 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPCHR:PC21G07170-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:Pc21g07170Imported, PCH_Pc21g07170Imported
    OrganismiPenicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)Imported
    Taxonomic identifieri500485 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
    ProteomesiUP000000724: Contig Pc00c21

    Interactioni

    Protein-protein interaction databases

    STRINGi500485.B6HK40.

    Structurei

    3D structure databases

    ProteinModelPortaliB6HK40.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10777.
    OMAiHMCPSTK.
    OrthoDBiEOG7QC84G.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00292. BRCT. 2 hits.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B6HK40-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSDEILGQD DVLKPEQEED LDEKYPNRPH NRAPTLPFHD LYLDLFNPLS    50
    ELKKKPSGPA PARRKAGPHG KGATSLNPFE RRRDVIERFI SRWRKDVGDD 100
    IYPALRLILP DKDRDRPMYG IKEKAIGRML VKIMKINKES EDGYNLLNWK 150
    LPGQGATTRM AGDFARRCFD VLSKRPMRTD PGDMTIEEVN EKLDKLSAAS 200
    KEDEQLPILT EFYRRMNPEE LLWLIRIILR QMKVGATERT FFDVWHPDAE 250
    NLYSISSSLR RVCWELHDPN IRLEGEERGI ALMQCFQPQL AQFQMHSFER 300
    IIARMKPTED DNVFWIEEKM DGERMQLHMA PDDSTKGGRK FGFWSRKAKE 350
    YTYLYGNGIY DENGALTRHL KDAFVDGVQS IILDGEMITW DPEQDAMVPF 400
    GTLKTAALAE QRNPFSNGPR PLFRVFDILH LNGRDLTKYT LRDRRNALEK 450
    TVRPVHRRFE IHSYEEATTT TEVEAALRKV VAEASEGLVL KNPRSPYRLN 500
    ERHDDWMKVK PDYMTEFGES LDVIVIGGYY GSGRRGGALS SFLCGLRVDD 550
    STQAAEKCWS FCKVGGGFTA ADYQEVRHHT DGKWKAWDAK KPPTTFVELA 600
    GGDAQHERPD MWIKPSDSIV LCVKAASVAI SDQFRMGLAL RFPRFKKLRK 650
    DKDWKTALSV QEFLDLKSNA EQEHREKEFS VDNSRKKRVK RATKKPLTVA 700
    GHEDNVDVQY LGPSGHVFDE LNFFIMTEST VPEKKTKLQL EQLVKANGGK 750
    IYQTKTAAVD TLCVAERRTV KVASLQKSGE QNIIRPSWLI DCVKQNEIDA 800
    GLPDLLLPFE PRHMFFMTEE KEEEVAANVD KFMDSYARDT TVNELKDADD 850
    VPDPETTQRI ETRIQERVNA GYTVPVGWLF RGLKFHFYSN GNQPDESASR 900
    EIRREDQRLQ FARNTARFAA AEIAKTLKSS GITHVIVDPE TVSSADKTSL 950
    RNTLAAKPGA KMPHLVSVGW VEECWKNGTL LDEERFPILR 990
    Length:990
    Mass (Da):113,516
    Last modified:December 16, 2008 - v1
    Checksum:i4ED51FADC197051E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM920436 Genomic DNA. Translation: CAP95614.1.
    RefSeqiXP_002567758.1. XM_002567712.1.

    Genome annotation databases

    GeneIDi8314155.
    KEGGipcs:Pc21g07170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM920436 Genomic DNA. Translation: CAP95614.1 .
    RefSeqi XP_002567758.1. XM_002567712.1.

    3D structure databases

    ProteinModelPortali B6HK40.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 500485.B6HK40.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8314155.
    KEGGi pcs:Pc21g07170.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10777.
    OMAi HMCPSTK.
    OrthoDBi EOG7QC84G.

    Enzyme and pathway databases

    BioCyci PCHR:PC21G07170-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00292. BRCT. 2 hits.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255Imported.

    Entry informationi

    Entry nameiB6HK40_PENCW
    AccessioniPrimary (citable) accession number: B6HK40
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 16, 2008
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3