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B6HK40

- B6HK40_PENCW

UniProt

B6HK40 - B6HK40_PENCW

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Protein

DNA ligase

Gene

Pc21g07170

Organism
Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPCHR:PC21G07170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Pc21g07170Imported, PCH_Pc21g07170Imported
OrganismiPenicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
ProteomesiUP000000724: Contig Pc00c21

Interactioni

Protein-protein interaction databases

STRINGi500485.B6HK40.

Structurei

3D structure databases

ProteinModelPortaliB6HK40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
KOiK10777.
OMAiHMCPSTK.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6HK40-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSDEILGQD DVLKPEQEED LDEKYPNRPH NRAPTLPFHD LYLDLFNPLS
60 70 80 90 100
ELKKKPSGPA PARRKAGPHG KGATSLNPFE RRRDVIERFI SRWRKDVGDD
110 120 130 140 150
IYPALRLILP DKDRDRPMYG IKEKAIGRML VKIMKINKES EDGYNLLNWK
160 170 180 190 200
LPGQGATTRM AGDFARRCFD VLSKRPMRTD PGDMTIEEVN EKLDKLSAAS
210 220 230 240 250
KEDEQLPILT EFYRRMNPEE LLWLIRIILR QMKVGATERT FFDVWHPDAE
260 270 280 290 300
NLYSISSSLR RVCWELHDPN IRLEGEERGI ALMQCFQPQL AQFQMHSFER
310 320 330 340 350
IIARMKPTED DNVFWIEEKM DGERMQLHMA PDDSTKGGRK FGFWSRKAKE
360 370 380 390 400
YTYLYGNGIY DENGALTRHL KDAFVDGVQS IILDGEMITW DPEQDAMVPF
410 420 430 440 450
GTLKTAALAE QRNPFSNGPR PLFRVFDILH LNGRDLTKYT LRDRRNALEK
460 470 480 490 500
TVRPVHRRFE IHSYEEATTT TEVEAALRKV VAEASEGLVL KNPRSPYRLN
510 520 530 540 550
ERHDDWMKVK PDYMTEFGES LDVIVIGGYY GSGRRGGALS SFLCGLRVDD
560 570 580 590 600
STQAAEKCWS FCKVGGGFTA ADYQEVRHHT DGKWKAWDAK KPPTTFVELA
610 620 630 640 650
GGDAQHERPD MWIKPSDSIV LCVKAASVAI SDQFRMGLAL RFPRFKKLRK
660 670 680 690 700
DKDWKTALSV QEFLDLKSNA EQEHREKEFS VDNSRKKRVK RATKKPLTVA
710 720 730 740 750
GHEDNVDVQY LGPSGHVFDE LNFFIMTEST VPEKKTKLQL EQLVKANGGK
760 770 780 790 800
IYQTKTAAVD TLCVAERRTV KVASLQKSGE QNIIRPSWLI DCVKQNEIDA
810 820 830 840 850
GLPDLLLPFE PRHMFFMTEE KEEEVAANVD KFMDSYARDT TVNELKDADD
860 870 880 890 900
VPDPETTQRI ETRIQERVNA GYTVPVGWLF RGLKFHFYSN GNQPDESASR
910 920 930 940 950
EIRREDQRLQ FARNTARFAA AEIAKTLKSS GITHVIVDPE TVSSADKTSL
960 970 980 990
RNTLAAKPGA KMPHLVSVGW VEECWKNGTL LDEERFPILR
Length:990
Mass (Da):113,516
Last modified:December 16, 2008 - v1
Checksum:i4ED51FADC197051E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920436 Genomic DNA. Translation: CAP95614.1.
RefSeqiXP_002567758.1. XM_002567712.1.

Genome annotation databases

GeneIDi8314155.
KEGGipcs:Pc21g07170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920436 Genomic DNA. Translation: CAP95614.1 .
RefSeqi XP_002567758.1. XM_002567712.1.

3D structure databases

ProteinModelPortali B6HK40.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 500485.B6HK40.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8314155.
KEGGi pcs:Pc21g07170.

Phylogenomic databases

eggNOGi COG1793.
KOi K10777.
OMAi HMCPSTK.
OrthoDBi EOG7QC84G.

Enzyme and pathway databases

BioCyci PCHR:PC21G07170-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
PANTHERi PTHR10459:SF7. PTHR10459:SF7. 1 hit.
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255Imported.

Entry informationi

Entry nameiB6HK40_PENCW
AccessioniPrimary (citable) accession number: B6HK40
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3