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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Pc20g06370

Organism
Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei136 – 1361SubstrateUniRule annotation
Active sitei262 – 2621Proton acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Enzyme and pathway databases

BioCyciPCHR:PC20G06370-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:Pc20g06370Imported, PCH_Pc20g06370Imported
OrganismiPenicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)Imported
Taxonomic identifieri500485 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum complex
ProteomesiUP000000724 Componenti: Contig Pc00c20

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi500485.XP_002563166.1.

Structurei

3D structure databases

ProteinModelPortaliB6HGH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni328 – 3292Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
KOiK00006.
OMAiCMISSLI.
OrthoDBiEOG7V76H7.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6HGH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQKHKVVVI GSGNWGSTIG KILAENTREH SDIFEEDVSM WVFEEDVDVP
60 70 80 90 100
DDGTLRDQLG DKPVKLTHAI NTAHQNIKYL PGIKLPDNLI ANPDLQDTVR
110 120 130 140 150
GATILVFNLP HQFMSKTLEQ IKGHHLPYAR AISCVKGVDI SEGTVKLYSE
160 170 180 190 200
LIMEKLGIYC GSLSGANIAS EVAAENLCET TIGYDGPPMD YKEPDGSSRD
210 220 230 240 250
NLIKVDKQRQ SKSSPSQLSL HRVPQNYPHV DSALLEKLFG RPYFNVQVVR
260 270 280 290 300
DVSGVALGGA LKNIVALAAG FVAGKGWGEN TKAAVIRIGI LEMVRFGCLW
310 320 330 340 350
FPQSVDERTF TKESAGIADV IASTSAGRNF HSACHAVEQG VTVDEIEKKE
360 370 380 390 400
LGGQKLQGTS TSRAVYEFLE KQGQLEKFPL FVFVHDILEE RTTMDALPGL

LIKGSKVMA
Length:409
Mass (Da):44,775
Last modified:December 16, 2008 - v1
Checksum:i5640FAD6636CFFF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920435 Genomic DNA. Translation: CAP85966.1.
RefSeqiXP_002563166.1. XM_002563120.1.

Genome annotation databases

GeneIDi8310734.
KEGGipcs:Pc20g06370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920435 Genomic DNA. Translation: CAP85966.1.
RefSeqiXP_002563166.1. XM_002563120.1.

3D structure databases

ProteinModelPortaliB6HGH0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi500485.XP_002563166.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8310734.
KEGGipcs:Pc20g06370.

Phylogenomic databases

eggNOGiCOG0240.
HOGENOMiHOG000246855.
KOiK00006.
OMAiCMISSLI.
OrthoDBiEOG7V76H7.

Enzyme and pathway databases

BioCyciPCHR:PC20G06370-MONOMER.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 28089 / DSM 1075 / Wisconsin 54-1255Imported.

Entry informationi

Entry nameiB6HGH0_PENCW
AccessioniPrimary (citable) accession number: B6HGH0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: July 22, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.