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B6HEK2 (B6HEK2_PENCW) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length788 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

Sequence similarities

Contains 1 SET domain.

Contains 1 post-SET domain. RuleBase RU004541

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Ontologies

Keywords
   Cellular componentNucleus SAAS SAAS001214
   LigandS-adenosyl-L-methionine SAAS SAAS001214
   Molecular functionMethyltransferase RuleBase RU004541 SAAS SAAS001214
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionhistone-lysine N-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B6HEK2 [UniParc].

Last modified December 16, 2008. Version 1.
Checksum: 19B0E70A567FD0AC

FASTA78886,467
        10         20         30         40         50         60 
MAPRTSRSVA SAAPDAQAHE PTDDNMSLDV PEQLLTPENS RSETSSNNEN ALADEKPAGR 

        70         80         90        100        110        120 
RRSTRVARAS LRPGEPLDDT NKEPAASSSE AYVDSLAKAK RSHSSLRHSI AVMESSLWSG 

       130        140        150        160        170        180 
APVDDDTVAD DTAAPDTPVS KSSQDLQSED MNTALQQRTL RKRVGKALVE DEGTPTAGVV 

       190        200        210        220        230        240 
PTRTSPRKSL RRSGRFSLMD KASDLVDRAS SILGKRTRGL ADKDLGRRAS LRPRNNAPSK 

       250        260        270        280        290        300 
DETALSAVNE PASKKRRVSE SDLSKLQDQD TPEPEEPAVS ASRPRKIWLS HGLYTGQEPS 

       310        320        330        340        350        360 
DSPPKQRRSK NSKKTGTGPM QRTILPMPMF KGARLLKTGR DYQLPYDIFS PLPPGQPKPN 

       370        380        390        400        410        420 
EWRKTNKNVF VGDAGSFWKA NKKLELSTCM CTEDTGCDEN CQNRYMFYEC DNGNCRLGPE 

       430        440        450        460        470        480 
CGNRNFEGLK QRTKAGGKYN IGVEVIKTAD RGYGVRSNRS FEPNQIIVEY TGEILTQLEC 

       490        500        510        520        530        540 
EKRMRTVYKN NDCYYLMYFD QNMIIDATRG SIARFVNHAC EPNCRMEKWT VAGKPRMALF 

       550        560        570        580        590        600 
AGDRGVSTGE ELSYDYNFDP YSNKNVQECR CGSANCRGFL GPRLKEKQQR AKELEKRKAE 

       610        620        630        640        650        660 
GSPKTTTAKK VIGKKRKASE EAESDDEAPQ GKKRKIIRSK SIKAGVKKAV AAVRGKKTTK 

       670        680        690        700        710        720 
TTAKGKTTTA VKSKTNVKLP TVKATGRIKA TVRASRSNKT AKETPASPKK TTSQLKRPSA 

       730        740        750        760        770        780 
ETKKKILATA SKGSGASPRK PAKRVPAKSP VKAKKPAPKA KSTPKGGFGK GVKSAARRVM 


KSVKGSKK 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM920435 Genomic DNA. Translation: CAP86099.1.
RefSeqXP_002563293.1. XM_002563247.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING500485.B6HEK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8313361.
KEGGpcs:Pc20g07700.

Phylogenomic databases

eggNOGCOG2940.
HOGENOMHOG000194167.
KOK06101.
OMAHSIAVME.
OrthoDBEOG7P8PH3.

Enzyme and pathway databases

BioCycPCHR:PC20G07700-MONOMER.

Family and domain databases

InterProIPR006560. AWS.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamPF00856. SET. 1 hit.
[Graphical view]
SMARTSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6HEK2_PENCW
AccessionPrimary (citable) accession number: B6HEK2
Entry history
Integrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)