Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-amyrin synthase

Gene

BAS

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Converts oxidosqualene to beta-amyrin.1 Publication

Catalytic activityi

(3S)-2,3-epoxy-2,3-dihydrosqualene = beta-amyrin.1 Publication

GO - Molecular functioni

  • beta-amyrin synthase activity Source: TAIR

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BRENDAi5.4.99.39. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-amyrin synthase (EC:5.4.99.39)
Short name:
AtBAS
Alternative name(s):
Lupeol synthase 4
Short name:
AtLUP4
Gene namesi
Name:BAS
Synonyms:LUP4
Ordered Locus Names:At1g78950
ORF Names:YUP8H12R.44
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G78950.
TAIRilocus:2207315. AT1G78950.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003661341 – 759Beta-amyrin synthaseAdd BLAST759

Proteomic databases

PaxDbiB6EXY6.

Expressioni

Gene expression databases

ExpressionAtlasiB6EXY6. baseline and differential.
GenevisibleiB6EXY6. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G78950.1.

Structurei

3D structure databases

ProteinModelPortaliB6EXY6.
SMRiB6EXY6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati149 – 190PFTB 1Add BLAST42
Repeati592 – 632PFTB 2Add BLAST41
Repeati641 – 682PFTB 3Add BLAST42

Sequence similaritiesi

Belongs to the terpene cyclase/mutase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0497. Eukaryota.
COG1657. LUCA.
HOGENOMiHOG000234317.
KOiK15813.
OMAiGHENACA.
OrthoDBiEOG0936031Q.
PhylomeDBiB6EXY6.

Family and domain databases

CDDicd02892. SQCY_1. 1 hit.
InterProiView protein in InterPro
IPR032696. SQ_cyclase_C.
IPR032697. SQ_cyclase_N.
IPR018333. Squalene_cyclase.
IPR002365. Terpene_synthase_CS.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
PfamiView protein in Pfam
PF13243. SQHop_cyclase_C. 1 hit.
PF13249. SQHop_cyclase_N. 1 hit.
SUPFAMiSSF48239. SSF48239. 2 hits.
TIGRFAMsiTIGR01787. squalene_cyclas. 1 hit.
PROSITEiView protein in PROSITE
PS01074. TERPENE_SYNTHASES. 1 hit.

Sequencei

Sequence statusi: Complete.

B6EXY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRLKIGEGN GDDPYLFTTN NFAGRQTWEF DPDGGSPEER HSVVEARRIF
60 70 80 90 100
YDNRFHVKAS SDLLWRMQFL REKKFEQRIA PVKVEDSEKV TFETATSALR
110 120 130 140 150
RGIHFFSALQ ASDGHWPAEN AGPLFFLPPL VFCLYITGHL DEVFTSEHRK
160 170 180 190 200
EILRYIYCHQ KEDGGWGLHI EGHSTMFCTT LNYICMRILG ESPDGGHDNA
210 220 230 240 250
CGRAREWILS HGGVTYIPSW GKTWLSILGV FDWSGSNPMP PEFWILPSFF
260 270 280 290 300
PVHPAKMWSY CRMVYLPMSY LYGKRFVGPI TSLILQLRKE LYLQPYEEIN
310 320 330 340 350
WMKVRHLCAK EDTYYPRPLV QELVWDSLYI FAEPFLARWP FNKLLREKAL
360 370 380 390 400
QLAMKHIHYE DENSRYITIG CVEKVLCMLA CWVEDPNGDY FKKHLSRISD
410 420 430 440 450
YLWMAEDGMK MQSFGSQLWD TGFAMQALLA SNLSSEISDV LRRGHEFIKN
460 470 480 490 500
SQVGENPSGD YKSMYRHISK GAWTFSDRDH GWQVSDCTAH GLKCCLLFSM
510 520 530 540 550
LAPDIVGPKQ DPERLHDSVN ILLSLQSKNG GMTAWEPAGA PKWLELLNPT
560 570 580 590 600
EMFSDIVIEH EYSECTSSAI QALSLFKQLY PDHRTTEITA FIKKAAEYLE
610 620 630 640 650
NMQTRDGSWY GNWGICFTYG TWFALAGLAA AGKTFNDCEA IRKGVQFLLA
660 670 680 690 700
AQKDNGGWGE SYLSCSKKIY IAQVGEISNV VQTAWALMGL IHSGQAERDP
710 720 730 740 750
IPLHRAAKLI INSQLESGDF PQQQATGVFL KNCTLHYAAY RNIHPLWALA

EYRARVSLP
Length:759
Mass (Da):86,953
Last modified:March 3, 2009 - v2
Checksum:iE8677A08B251C33D
GO

Sequence cautioni

The sequence AAC17080 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At1g78950 has been split into 2 genes: At1g78950 and At1g78955.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti334P → L in BAG82628 (PubMed:18977664).Curated1
Sequence conflicti544L → S in BAG82628 (PubMed:18977664).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB374428 mRNA. Translation: BAG82628.1.
AC002986 Genomic DNA. Translation: AAC17080.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE36183.1.
PIRiT01060.
RefSeqiNP_178016.2. NM_106544.5.
UniGeneiAt.34208.

Genome annotation databases

EnsemblPlantsiAT1G78950.1; AT1G78950.1; AT1G78950.
GeneIDi844234.
GrameneiAT1G78950.1; AT1G78950.1; AT1G78950.
KEGGiath:AT1G78950.

Similar proteinsi

Entry informationi

Entry nameiLUP4_ARATH
AccessioniPrimary (citable) accession number: B6EXY6
Secondary accession number(s): O64553, Q3ECA8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 27, 2017
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families