Reviewed, UniProtKB/Swiss-Prot B6ENG3 (DEOC_ALISL)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	VSAL_I0619

Organism

Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]

Taxonomic identifier

316275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00592
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00592
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	Deoxyribose-phosphate aldolase HAMAP MF_00592		PRO_1000129798
Sites
	Active site	165	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	199	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B6ENG3-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 49539D145B83AAE2	FASTA	258	27,563
	10 20 30 40 50 60 MSDLKAAALR ALKLMDLTTL NDNDTDEAVI ALCKNAKTAV GNTAAVCIYP RFVPIAKKTL 70 80 90 100 110 120 REQGTPDVRI ATVTNFPHGN DDIAIAVAET KAAVAYGADE VDVVFPYRAL IAGNETVGFE 130 140 150 160 170 180 LVKQCKEACG DILLKVIIET GELKEEALIK KTSQICIEAG ANFIKTSTGK VPVNATPEYA 190 200 210 220 230 240 RMMLEVIRDM GVAKTVGFKP AGGVRTAEDA QAYLAMADDI LGGDWADNMH YRFGASSLLT 250 NLLNTLEVTA ETADPSAY

References

[1]

"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238." Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	FM178379 Genomic DNA. Translation: CAQ78304.1.
RefSeq	YP_002262139.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6986572.
GenomeReviews	Gene locus VSAL_I0619 in contig FM178379_GR.
KEGG	vsa:VSAL_I0619.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CKEACGD.
Family and domain databases
HAMAP	MF_00592. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_ALISL

Accession

Primary (citable) accession number: B6ENG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)