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B6EN80 (MTLD_ALISL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:VSAL_I2814
OrganismAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]
Taxonomic identifier316275 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000099188

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
B6EN80 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 81B963507DDE9D2C

FASTA38242,107
        10         20         30         40         50         60 
MKAVHFGAGN IGRGFIGKVL SDSNVAVTFA DVDAPLVDQL CHDQSYKVKV VGSKCQIDTV 

        70         80         90        100        110        120 
THVTAVNSTS DDVIERIVHT DLVTTAVGPN VLNIIAKTIA KGLTKRFEAN NESPLNIIAC 

       130        140        150        160        170        180 
ENMVRGTTHL KNEVYSHLDD SFHARCDELV GFVDSAVDRI VPPSEAANDD LLEVTVESFS 

       190        200        210        220        230        240 
EWIVDEKQFK GGVPNIAGME KTDNLMAFVE RKLFTLNTGH CITAYLGALK GHETVRDAIQ 

       250        260        270        280        290        300 
DPEIRTEVKA AMEESGEVLI RRYGFDKELH AAYIEKILGR FANPYLRDEI DRVARQPIRK 

       310        320        330        340        350        360 
LGENDRLIKP LLGTIEYGIE NKTLLKGIAA AFKYVNDTDP QAVELQTHLQ ESGLKATLAH 

       370        380 
YTGLNENSSE AKKIEAIFTT LN

« Hide

References

[1]"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238."
Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LFI1238.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM178379 Genomic DNA. Translation: CAQ80498.1.
RefSeqYP_002264148.1. NC_011312.1.

3D structure databases

ProteinModelPortalB6EN80.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6EN80.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6988854.
GenomeReviewsGene locus VSAL_I2814 in contig FM178379_GR.
KEGGvsa:VSAL_I2814.
PATRIC20856142. VBIAliSal95923_3049.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_ALISL
AccessionPrimary (citable) accession number: B6EN80
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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