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B6EMU2 (GLSA_ALISL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:VSAL_I0536
OrganismAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]
Taxonomic identifier316275 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Glutaminase HAMAP-Rule MF_00313
PRO_1000115691

Sites

Binding site641Substrate By similarity
Binding site1151Substrate By similarity
Binding site1591Substrate By similarity
Binding site1661Substrate By similarity
Binding site1901Substrate By similarity
Binding site2421Substrate By similarity
Binding site2601Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
B6EMU2 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: A515E40E44ED276B

FASTA30633,482
        10         20         30         40         50         60 
MKPTKQILED ILNEVRPLIG QGEVADYIPA LACVPSNKLG IAVYTNDGEM ITAGDANERF 

        70         80         90        100        110        120 
SIQSISKALS LTLAMELYQP EELWHRVGKE PSGQAFNSLI QLEMEQGVPR NPFINAGAIV 

       130        140        150        160        170        180 
VADMLFSRFS APKHRLLEFV RKLSGNEHII YDRVVANSEM DHSDRNASIA YLMRSFGNFE 

       190        200        210        220        230        240 
NEVMPVLKNY FHACSLNMSC VDLAKTFGYL ANKGIQPETN EFIITPMQSK QINALMATCG 

       250        260        270        280        290        300 
LYDGAGEFAY RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TQALELLSER 


IGRSIF 

« Hide

References

[1]"The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay."
Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.P., Thomson N.R.
BMC Genomics 9:616-616(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LFI1238.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM178379 Genomic DNA. Translation: CAQ78221.1.
RefSeqYP_002262057.1. NC_011312.1.

3D structure databases

ProteinModelPortalB6EMU2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316275.VSAL_I0536.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAQ78221; CAQ78221; VSAL_I0536.
GeneID6989321.
KEGGvsa:VSAL_I0536.
PATRIC20851177. VBIAliSal95923_0644.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAMSIAVWS.
OrthoDBEOG6N94BK.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_ALISL
AccessionPrimary (citable) accession number: B6EMU2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families