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Protein

Glutaminase

Gene

glsA

Organism
Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641SubstrateUniRule annotation
Binding sitei115 – 1151SubstrateUniRule annotation
Binding sitei159 – 1591SubstrateUniRule annotation
Binding sitei166 – 1661SubstrateUniRule annotation
Binding sitei190 – 1901SubstrateUniRule annotation
Binding sitei242 – 2421SubstrateUniRule annotation
Binding sitei260 – 2601Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:VSAL_I0536
OrganismiAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
Taxonomic identifieri316275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
ProteomesiUP000001730 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminasePRO_1000115691Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi316275.VSAL_I0536.

Structurei

3D structure databases

ProteinModelPortaliB6EMU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B6EMU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPTKQILED ILNEVRPLIG QGEVADYIPA LACVPSNKLG IAVYTNDGEM
60 70 80 90 100
ITAGDANERF SIQSISKALS LTLAMELYQP EELWHRVGKE PSGQAFNSLI
110 120 130 140 150
QLEMEQGVPR NPFINAGAIV VADMLFSRFS APKHRLLEFV RKLSGNEHII
160 170 180 190 200
YDRVVANSEM DHSDRNASIA YLMRSFGNFE NEVMPVLKNY FHACSLNMSC
210 220 230 240 250
VDLAKTFGYL ANKGIQPETN EFIITPMQSK QINALMATCG LYDGAGEFAY
260 270 280 290 300
RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TQALELLSER

IGRSIF
Length:306
Mass (Da):33,482
Last modified:November 25, 2008 - v1
Checksum:iA515E40E44ED276B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM178379 Genomic DNA. Translation: CAQ78221.1.
RefSeqiWP_012549345.1. NC_011312.1.
YP_002262057.1. NC_011312.1.

Genome annotation databases

EnsemblBacteriaiCAQ78221; CAQ78221; VSAL_I0536.
KEGGivsa:VSAL_I0536.
PATRICi20851177. VBIAliSal95923_0644.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM178379 Genomic DNA. Translation: CAQ78221.1.
RefSeqiWP_012549345.1. NC_011312.1.
YP_002262057.1. NC_011312.1.

3D structure databases

ProteinModelPortaliB6EMU2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316275.VSAL_I0536.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAQ78221; CAQ78221; VSAL_I0536.
KEGGivsa:VSAL_I0536.
PATRICi20851177. VBIAliSal95923_0644.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay."
    Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.P., Thomson N.R.
    BMC Genomics 9:616-616(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LFI1238.

Entry informationi

Entry nameiGLSA_ALISL
AccessioniPrimary (citable) accession number: B6EMU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: May 27, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.