Reviewed, UniProtKB/Swiss-Prot B6EMR5 (PSD_ALISL)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	VSAL_I2785

Organism

Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]

Taxonomic identifier

316275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 252	252	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000131332
	Chain	253 – 287	35	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000131333
Sites
	Site	252 – 253	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	253	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	B6EMR5-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 4979A4252B685EC5	FASTA	287	31,577
	10 20 30 40 50 60 MSDNLKIGLQ YLTPKHALTR LAGKLASAKM GWLTTAVIKW FIKQYNVEMS EAKNPDPEAY 70 80 90 100 110 120 STFNNFFVRE LEDGARPIND DENVISHPAD ACVSQFGPIT DGQLVQAKGH VYSAQELLGG 130 140 150 160 170 180 DAELAEEFIG GEFATLYLSP RDYHRVHMPC DATLRKMVYV PGDLFSVNPL TAENVPNLFA 190 200 210 220 230 240 RNERVVCIFD TEFGPMAQVL VGATIVGSIE TTWADTVTPP TGPAVKTWHY PLSGDDVICF 250 260 270 280 KKGEEMGRFK LGSTVINLFA PNSITFDESM KNGVPTRLGT PFAHIAK

References

[1]

"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238." Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	FM178379 Genomic DNA. Translation: CAQ80469.1.
RefSeq	YP_002264121.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6987916.
GenomeReviews	Gene locus VSAL_I2785 in contig FM178379_GR.
KEGG	vsa:VSAL_I2785.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YVPGRLF.
Family and domain databases
HAMAP	MF_00662. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_ALISL

Accession

Primary (citable) accession number: B6EMR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)