Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B6EJW7

- LPXB_ALISL

UniProt

B6EJW7 - LPXB_ALISL

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (25 Nov 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:VSAL_I2414
    OrganismiAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
    Taxonomic identifieri316275 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
    ProteomesiUP000001730: Chromosome 1

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 383383Lipid-A-disaccharide synthasePRO_1000191458Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi316275.VSAL_I2414.

    Structurei

    3D structure databases

    ProteinModelPortaliB6EJW7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018003.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B6EJW7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKPLRIGIV AGELSGDTLG EGFIKSVKAQ YPNAEFVGIG GPKMIAQGCE    50
    SLFDMEELAV MGLVEVLGRL PRLLKVKAEL VRYFSQNPPD VFIGIDAPDF 100
    NLRLEKTLKD SGIKTVHYVS PSVWAWRPKR IFKIDAATDL VLAFLPFEKV 150
    FYDKYNVACE FIGHTLADAI PMQSDKIAAR KLLGLELDRQ WLAVLPGSRG 200
    GEVALIAKPF IETCQRIHQK HPNMGFVVAA VNEKRREQFE VIWKETAPEL 250
    KFIIIQDTAR NVMTAADSVL LASGTVALEC MLIKRPMVVG YQVNKLTGWI 300
    AQKLSITEFV SLPNVLAGKE LVQEFIQEEC HPDFLYPAME KVLSQDNSEL 350
    IDRFTEMHQW IKKDADKQAA NAVLRLINKE TAE 383
    Length:383
    Mass (Da):42,929
    Last modified:November 25, 2008 - v1
    Checksum:i1DEC4146FE77622D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM178379 Genomic DNA. Translation: CAQ80098.1.
    RefSeqiWP_012550902.1. NC_011312.1.
    YP_002263768.1. NC_011312.1.

    Genome annotation databases

    EnsemblBacteriaiCAQ80098; CAQ80098; VSAL_I2414.
    GeneIDi6989138.
    KEGGivsa:VSAL_I2414.
    PATRICi20855249. VBIAliSal95923_2629.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM178379 Genomic DNA. Translation: CAQ80098.1 .
    RefSeqi WP_012550902.1. NC_011312.1.
    YP_002263768.1. NC_011312.1.

    3D structure databases

    ProteinModelPortali B6EJW7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316275.VSAL_I2414.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAQ80098 ; CAQ80098 ; VSAL_I2414 .
    GeneIDi 6989138.
    KEGGi vsa:VSAL_I2414.
    PATRICi 20855249. VBIAliSal95923_2629.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018003.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay."
      Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.P., Thomson N.R.
      BMC Genomics 9:616-616(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LFI1238.

    Entry informationi

    Entry nameiLPXB_ALISL
    AccessioniPrimary (citable) accession number: B6EJW7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3