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B6EIX8 (AROA_ALISL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:VSAL_I2218
OrganismAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]
Taxonomic identifier316275 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4274273-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099662

Sequences

Sequence LengthMass (Da)Tools
B6EIX8 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: CA17B98A10E374A6

FASTA42745,749
        10         20         30         40         50         60 
MESLTLQPIS KIDGQINLPG SKSVSNRALL LAALASGKTT LTNLLDSDDI RHMLNALKAL 

        70         80         90        100        110        120 
GVDYKLSEDK TVCEVNGLGQ AFKSTTEALE LFLGNAGTAM RPLAAALCLG EGEFILTGEP 

       130        140        150        160        170        180 
RMKERPIGHL VTALKAAGAD VEYLENENYP PLKIKGTGLK GGNVDIDGSI SSQFLTAFLM 

       190        200        210        220        230        240 
AAPLSSQETT INIVGDLVSK PYIDITLDIM ATFGVVIENK EYKTFVVPAN QSYIAPGEFL 

       250        260        270        280        290        300 
VEGDASSASY FLAAAAIKGG SVKVTGIGKK SIQGDVQFAD ALAAMGAEIE WGDDYVIAHK 

       310        320        330        340        350        360 
GELNAIDMDF NHIPDAAMTI ATTALFAKGT TSIRNVYNWR VKETDRLAAM ATELRKVGAE 

       370        380        390        400        410        420 
VEEGEDYITI TPPAMLRHAT IDTYDDHRMA MCFSLVALSD TPVTINDPGC TSKTFPDYFD 


KLKELSV

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References

[1]"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238."
Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LFI1238.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM178379 Genomic DNA. Translation: CAQ79903.1.
RefSeqYP_002263584.1. NC_011312.1.

3D structure databases

ProteinModelPortalB6EIX8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6EIX8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6988208.
GenomeReviewsGene locus VSAL_I2218 in contig FM178379_GR.
KEGGvsa:VSAL_I2218.
PATRIC20854829. VBIAliSal95923_2419.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAGADIEWG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_ALISL
AccessionPrimary (citable) accession number: B6EIX8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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