B6EIC1 (RLMG_ALISL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	VSAL_I0947

Organism

Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]

Taxonomic identifier

316275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 382	382	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366447

Sequences

	Sequence		Length	Mass (Da)
	B6EIC1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 0F5D26FADE64B112	FASTA	382	43,624
	10 20 30 40 50 60 MKTELCLFDR TLNLQRYPKR AQELLQAWDA GDEFIIKHVE EELNLEDNKN ILILNDNFGA 70 80 90 100 110 120 LSCWFSEKHN VTMMTDSFVS QRGTLKNLQR NQCNRVQLIS STEEMPEGFD LVIMQIPKNN 130 140 150 160 170 180 RMLAWQLQQL RQSMTAECPI IAVNKAKEIH SSTLEVFEDY LGETKTSLAW KKHRLVFSNA 190 200 210 220 230 240 NATNPLTIAE AVCWSVDNED IDLLNYPNVY SGERLDQGAR FMLEHIPVDA ELRHIIDLGC 250 260 270 280 290 300 GNGVLSVKAA QLNPEARITC IDESFMAVES ARRNLEVNLG KERQFQFIAN NCLDGFKKHS 310 320 330 340 350 360 SYLVLCNPPF HQGQAVTDHI AWQMFCDAKH ILCKEGKLLV IGNRHLDYDD KLCRLFGEEN 370 380 VTTIASNSKF VILEAVKAEK SK

References

[1]

"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238." Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LFI1238.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM178379 Genomic DNA. Translation: CAQ78632.1.
RefSeq	YP_002262442.1. NC_011312.1.
3D structure databases
ProteinModelPortal	B6EIC1.
ModBase	Search...
Protein-protein interaction databases
STRING	B6EIC1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6986740.
GenomeReviews	Gene locus VSAL_I0947 in contig FM178379_GR.
KEGG	vsa:VSAL_I0947.
PATRIC	20852090. VBIAliSal95923_1072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG321931.
OMA	NRHLGYH.
ProtClustDB	CLSK874746.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_ALISL

Accession

Primary (citable) accession number: B6EIC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program