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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:VSAL_I0947
OrganismiAliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))
Taxonomic identifieri316275 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
Proteomesi
  • UP000001730 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 382382Ribosomal RNA large subunit methyltransferase GPRO_0000366447Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316275.VSAL_I0947.

Structurei

3D structure databases

ProteinModelPortaliB6EIC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR013675. Mtase_sm_N.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

B6EIC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTELCLFDR TLNLQRYPKR AQELLQAWDA GDEFIIKHVE EELNLEDNKN
60 70 80 90 100
ILILNDNFGA LSCWFSEKHN VTMMTDSFVS QRGTLKNLQR NQCNRVQLIS
110 120 130 140 150
STEEMPEGFD LVIMQIPKNN RMLAWQLQQL RQSMTAECPI IAVNKAKEIH
160 170 180 190 200
SSTLEVFEDY LGETKTSLAW KKHRLVFSNA NATNPLTIAE AVCWSVDNED
210 220 230 240 250
IDLLNYPNVY SGERLDQGAR FMLEHIPVDA ELRHIIDLGC GNGVLSVKAA
260 270 280 290 300
QLNPEARITC IDESFMAVES ARRNLEVNLG KERQFQFIAN NCLDGFKKHS
310 320 330 340 350
SYLVLCNPPF HQGQAVTDHI AWQMFCDAKH ILCKEGKLLV IGNRHLDYDD
360 370 380
KLCRLFGEEN VTTIASNSKF VILEAVKAEK SK
Length:382
Mass (Da):43,624
Last modified:November 25, 2008 - v1
Checksum:i0F5D26FADE64B112
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM178379 Genomic DNA. Translation: CAQ78632.1.
RefSeqiWP_012549717.1. NC_011312.1.

Genome annotation databases

EnsemblBacteriaiCAQ78632; CAQ78632; VSAL_I0947.
KEGGivsa:VSAL_I0947.
PATRICi20852090. VBIAliSal95923_1072.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM178379 Genomic DNA. Translation: CAQ78632.1.
RefSeqiWP_012549717.1. NC_011312.1.

3D structure databases

ProteinModelPortaliB6EIC1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316275.VSAL_I0947.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAQ78632; CAQ78632; VSAL_I0947.
KEGGivsa:VSAL_I0947.
PATRICi20852090. VBIAliSal95923_1072.

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR013675. Mtase_sm_N.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMG_ALISL
AccessioniPrimary (citable) accession number: B6EIC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.