Reviewed, UniProtKB/Swiss-Prot B6EHH0 (PTH_ALISL)

Names and origin

Protein names

Recommended name:
    Peptidyl-tRNA hydrolase
      Short name=PTH
    EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	VSAL_I0785

Organism

Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) [Complete proteome] [HAMAP]

Taxonomic identifier

316275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the PTH family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Peptidyl-tRNA hydrolase HAMAP MF_00083		PRO_1000092904

Sequences

	Sequence		Length	Mass (Da)
	B6EHH0-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: FE9B1BCE1C7BAFCD	FASTA	196	21,640
	10 20 30 40 50 60 MSNQIKLLVG LANPGLEYKR TRHNAGAWVV EELARIHNIP MREEAKFFGL TGRIQTNGQD 70 80 90 100 110 120 LRLLIPTTFM NLSGKAIASI AKFYQIKPEE ILVAHDELDL PPGVAKFKKG GGHGGHNGLR 130 140 150 160 170 180 DTISKLANTK EFYRLRIGIG HPGHKDKVAG FVLGKAPTKE QELIDAAVDE STRCLDILLK 190 DGLSKAQNRL HTFKAE

References

[1]

"The complete genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238." Hjerde E., Lorentzen M.S., Holden M.T.G., Seeger K., Paulsen S., Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S., Thurston S., Parkhill J., Willassen N.-P., Thomson N.R. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	FM178379 Genomic DNA. Translation: CAQ78470.1.
RefSeq	YP_002262295.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6988441.
GenomeReviews	Gene locus VSAL_I0785 in contig FM178379_GR.
KEGG	vsa:VSAL_I0785.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IKFKTGG.
Family and domain databases
HAMAP	MF_00083. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
TIGRFAMs	TIGR00447. pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTH_ALISL

Accession

Primary (citable) accession number: B6EHH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)