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B6A0D5

- B6A0D5_RHILW

UniProt

B6A0D5 - B6A0D5_RHILW

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Protein

Alanine racemase

Gene
Rleg2_4830
Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei150 – 1501Substrate By similarityUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciRLEG395492:GJB3-4896-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Rleg2_4830Imported
Encoded oniPlasmid pRLG201Imported
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)Imported
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000008330: Plasmid pRLG201

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 511N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi395492.Rleg2_4830.

Structurei

3D structure databases

ProteinModelPortaliB6A0D5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031445.
KOiK01775.
OMAiFIMSHLA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B6A0D5-1 [UniParc]FASTAAdd to Basket

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MDSDILVSRT RTNTTAQGAT GYLTIDLAAL GRNYRKLVSM LAPVRAGAVV    50
KANAYGLGAE RVATTLYGEG CRHFFVAQFV EAVRLRPTLA RDAQIFVLNG 100
LQPGNEIACA ERGIVPVLNS LTQWRQWSAT ARMLKRCLPA VLQFDTGMSR 150
LGFPEEERSE LAAALGDGSN VEILFIMSHL ASADDMESDQ NGEQLAEMAR 200
IADEFPGFDI SFANSGGVFL GDAYHGVLAR PGIALYGGAP HAGGNNPMEP 250
VVSLDVAVVQ TRTVPAGAKV GYGGAHVTQR KMRLATIAAG YADGLPRSLG 300
DRGAVYYNDI RLPIVGRVSM DSATVDVSAL PEGALTLGSL VEVLGSNQTL 350
EHIARDAGTI SYEILTGLGD RYDKQYR 377
Length:377
Mass (Da):40,193
Last modified:November 25, 2008 - v1
Checksum:i5BE6DE4C3E44C82F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001192 Genomic DNA. Translation: ACI58069.1.
RefSeqiYP_002278809.1. NC_011368.1.

Genome annotation databases

EnsemblBacteriaiACI58069; ACI58069; Rleg2_4830.
GeneIDi6977924.
KEGGirlt:Rleg2_4830.
PATRICi23122221. VBIRhiLeg95088_0962.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001192 Genomic DNA. Translation: ACI58069.1 .
RefSeqi YP_002278809.1. NC_011368.1.

3D structure databases

ProteinModelPortali B6A0D5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395492.Rleg2_4830.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI58069 ; ACI58069 ; Rleg2_4830 .
GeneIDi 6977924.
KEGGi rlt:Rleg2_4830.
PATRICi 23122221. VBIRhiLeg95088_0962.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031445.
KOi K01775.
OMAi FIMSHLA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci RLEG395492:GJB3-4896-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of plasmid 1 of Rhizobium leguminosarum bv. trifolii WSM2304."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R.
    , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM2304.

Entry informationi

Entry nameiB6A0D5_RHILW
AccessioniPrimary (citable) accession number: B6A0D5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: July 9, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, PlasmidImported

External Data

Dasty 3

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