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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:Rleg2_2768
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008330 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000929751 – 243Peptidyl-tRNA hydrolaseAdd BLAST243

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi395492.Rleg2_2768

Structurei

3D structure databases

ProteinModelPortaliB5ZY55
SMRiB5ZY55
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

B5ZY55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIIAGLGNP GGKYAGNRHN IGFMAVDAIH RRHSFSPWSK KFRAEIAEGE
60 70 80 90 100
LGGEKVLLIK PQTFMNLSGE AVGEAMRFYK LQPADLVAIY DELDLPAGKA
110 120 130 140 150
RLKTGGGHGG HNGIKSLDAH CGKEYRRLRL GIGHPGIKEM VQNHVLGDFA
160 170 180 190 200
KADKAWLEPL LDTLADNADM LVRNEDSQLM NKIALALGGK AEEEKPRKDN
210 220 230 240
KTTEKKPAGQ SHIHQARNHN QPKVLTTGPM ADILKKMFGN KGE
Length:243
Mass (Da):26,598
Last modified:November 25, 2008 - v1
Checksum:i3ABA9B144D43056C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001191 Genomic DNA Translation: ACI56038.1
RefSeqiWP_012558501.1, NC_011369.1

Genome annotation databases

EnsemblBacteriaiACI56038; ACI56038; Rleg2_2768
GeneIDi34192854
KEGGirlt:Rleg2_2768

Similar proteinsi

Entry informationi

Entry nameiPTH_RHILW
AccessioniPrimary (citable) accession number: B5ZY55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health