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B5ZWU4 (PNCB_RHILW) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Rleg2_4138
OrganismRhizobium leguminosarum bv. trifolii (strain WSM2304) [Complete proteome] [HAMAP]
Taxonomic identifier395492 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000129481

Sequences

Sequence LengthMass (Da)Tools
B5ZWU4 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 91C19449C3BFA88E

FASTA43449,509
        10         20         30         40         50         60 
MARTDIARRV YNHAWKLDPI IRSLIDTDFY KLLMLQMIWK LYPDVNASFT LINRTKRVRL 

        70         80         90        100        110        120 
ADEIDEGELR EQLDHARTLK LSKKEMIWLA GNSFYGRAQI FEPEFLAWLS NFQLPEYELS 

       130        140        150        160        170        180 
KKDGQYVLDF HGSWKETTMW EIPALAIVNE LRSRSAMRAL GPFTLDVLYA RAKAKMWSKV 

       190        200        210        220        230        240 
ERLKELPGLR ISDFGTRRRH SFLWQRWCVE ALKEGIGPAF TGTSNVLLAM DSDLEAVGTN 

       250        260        270        280        290        300 
AHELPMVAAA LAQTDEQLRN APYKILRDWN KLYGGNLLIV LPDAFGTAAF LRDAPEWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIEGGEKIID WWKKMGRDPR QKLLIFSDGL DVDAIIDTYR HFEGRVRMSF 

       370        380        390        400        410        420 
GWGTNLTNDF SGCAPTEISG LNPISVVCKV SDADGRPAVK LSDNPQKATG DPAEVERYLK 

       430 
FFGAEDRIDQ TVLV 

« Hide

References

[1]"Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R. expand/collapse author list , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WSM2304.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001191 Genomic DNA. Translation: ACI57400.1.
RefSeqYP_002283626.1. NC_011369.1.

3D structure databases

ProteinModelPortalB5ZWU4.
SMRB5ZWU4. Positions 1-426.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING395492.Rleg2_4138.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI57400; ACI57400; Rleg2_4138.
GeneID6982910.
KEGGrlt:Rleg2_4138.
PATRIC23132612. VBIRhiLeg95088_6098.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycRLEG395492:GJB3-4202-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_RHILW
AccessionPrimary (citable) accession number: B5ZWU4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways