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B5ZV62 (B5ZV62_RHILW) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898
Gene names
Name:gyrB HAMAP MF_01898
Ordered Locus Names:Rleg2_3946
OrganismRhizobium leguminosarum bv. trifolii (strain WSM2304) [Complete proteome] [HAMAP]
Taxonomic identifier395492 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length811 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898

Subcellular location

Cytoplasm By similarity HAMAP MF_01898.

Sequence similarities

Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380

Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Sequences

Sequence LengthMass (Da)Tools
B5ZV62 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 5589EFA00218488F

FASTA81189,079
        10         20         30         40         50         60 
MSDTSATENG VSTEYGADSI KVLKGLDAVR KRPGMYIGDT DDGSGLHHMV YEVVDNAIDE 

        70         80         90        100        110        120 
ALAGHADIVT VTLNPDGSVT VTDNGRGIPT DIHTGEGVSA AEVIMTQLHA GGKFDQNSYK 

       130        140        150        160        170        180 
VSGGLHGVGV SVVNALSVWL KLKIRRQGKI HEMSFTHGVA DAPLKVTGEA PNETGTEVSF 

       190        200        210        220        230        240 
MPSTDTFTMT EFDYGTLEHR LRELAFLNSG VRILLTDKRH SDIKQEELRY DGGLEAFVAY 

       250        260        270        280        290        300 
LDRAKKSLVD KPVAIRGEKD GITVEVAMWW NDSYHENVLC FTNNIPQRDG GTHMAGFRAA 

       310        320        330        340        350        360 
LTRQVVSYAD SSGITKREKV TLQGEDCREG LTAVLSVKVP DPKFSSQTKD KLVSSEVRPV 

       370        380        390        400        410        420 
VESLVNEALN TWFEEHPSEA KILVGKVVEA AAAREAARKA RELTRRKGAL DIASLPGKLA 

       430        440        450        460        470        480 
DCSERDPTKS EVFLVEGDSA GGSAKQGRSR ENQAILPLRG KILNVERARF DKMLSSQEIG 

       490        500        510        520        530        540 
TLITALGTGI GKDEFNVEKL RYHKIIIMTD ADVDGAHIRT LLLTFFFRQM PELIERGHLY 

       550        560        570        580        590        600 
IAQPPLYKVS RGKSVQYLKD EKALEEYLIS QGLEDAALKL GSGEVRTGQD LREVILDALR 

       610        620        630        640        650        660 
MRALLDNLHS RYNRAAIEQA AIAGALNAER VSDRARAQAL TSEVASRLDI IAEETERGWQ 

       670        680        690        700        710        720 
GDLTSDGGLR LERMVRGVKE IVVLDMALIG SSDARHIDQL TSRLKEIYQT PPSLHRREGD 

       730        740        750        760        770        780 
LEISGPRALL DAIFATGRKG LTMQRYKGLG EMNAEQLWET TLDPNVRSLL QVKVPDATDA 

       790        800        810 
DGLFARLMGD EVEPRREFIQ DNALSVANLD I

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References

[1]"Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R. expand/collapse author list , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WSM2304.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001191 Genomic DNA. Translation: ACI57208.1.
RefSeqYP_002283434.1. NC_011369.1.

3D structure databases

ProteinModelPortalB5ZV62.
SMRB5ZV62. Positions 20-389.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5ZV62.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6982710.
GenomeReviewsGene locus Rleg2_3946 in contig CP001191_GR.
KEGGrlt:Rleg2_3946.
PATRIC23132186. VBIRhiLeg95088_5892.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG304889.
OMADCSSRDP.
ProtClustDBPRK14939.

Family and domain databases

HAMAPMF_01898. GyrB.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR011557. GyrB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR001241. Topo_IIA.
IPR013759. Topo_IIA_B/N_ab.
IPR002288. Topo_IIA_B_C.
IPR013506. Topo_IIA_bsu_dom2.
IPR013760. Topo_IIA_cen.
IPR018522. TopoIIA_CS.
IPR006171. Toprim_domain.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KOK02470.
PfamPF00204. DNA_gyraseB. 1 hit.
PF00986. DNA_gyraseB_C. 1 hit.
PF02518. HATPase_c. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSPR00418. TPI2FAMILY.
SMARTSM00387. HATPase_c. 1 hit.
SM00433. TOP2c. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01059. GyrB. 1 hit.
PROSITEPS00177. TOPOISOMERASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5ZV62_RHILW
AccessionPrimary (citable) accession number: B5ZV62
Entry history
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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